探究血清降钙素原、白细胞介素6、内毒素联合检测诊断老年呼吸道细菌性感染的临床价值  

Exploring the Clinical Value of Combined Detection of Serum Procalcitonin,Interleukin 6,and Endotoxin in the Diagnosis of Elderly Respiratory Bacterial Infections

作　　者：徐娣 尹寒冰 张善虎 XU Di;YIN Hanbing;ZHANG Shanhu(Department of Laboratory,Shenxian People's Hospital of Liaocheng,Liaocheng 252400,Shandong,China)

机构地区：[1]聊城市莘县人民医院检验科,山东聊城252400

出　　处：《系统医学》2024年第22期71-74,共4页Systems Medicine

摘　　要：目的分析老年呼吸道细菌性感染诊断时使用降钙素原(procalcitonin,PCT)、白细胞介素6(interleukin 6,IL-6)、内毒素联合检测的诊断价值。方法非随机选取2022年2月—2023年2月莘县人民医院收治的老年呼吸道感染患者80例和健康体检者20名为研究对象。健康体检者为对照组,老年呼吸道感染患者依据是否感染细菌分为研究一组与研究二组,每组40例。比较受检者PCT、IL-6、内毒素水平,对比指标单独与联合检测的诊断效能。结果3组PCT、IL-6、内毒素比较,差异有统计学意义(P均<0.05)。联合检测的灵敏度为100.00%(40/40)、准确度为97.00%(97/100)、阴性预测值为100.00%(57/57),均高于单独检测,差异有统计学意义(χ^(2)=7.364、3.954、4.694,P均<0.05)。结论PCT、IL-6、内毒素联合诊断老年呼吸道细菌性感染的诊断效能高。Objective To analyze the diagnostic value of using combined procalcitonin(PCT),interleukin 6(IL-6),and endotoxin tests for the diagnosis of respiratory bacterial infections in the elderly.Methods Eighty cases of elderly patients with respiratory tract infections admitted to Shenxian People's Hospital from February 2022 to February 2023 and twenty healthy medical examiners were selected non-randomly as the study subjects.The healthy medical checkups were the control group,and the elderly patients with respiratory tract infections were divided into study group 1 and study group 2 according to whether they were infected with bacteria or not,with forty cases in each group.PCT,IL-6,and endotoxin levels were compared,and the diagnostic efficacy of the indicators alone and in combination was compared.Results There were statistically significant differences in the comparison of PCT,IL-6,and endotoxin among the 3 groups(all P<0.05).The sensitivity of the combined test was 100.00%(40/40),the accuracy was 97.00%(97/100),and the negative predictive value was 100.00%(57/57),which were higher than those of the separate test,and the differences were statistically significant(χ^(2)=7.364,3.954,4.694,all P<0.05).Conclusion The diagnostic efficacy of the combination of PCT,IL-6,and endotoxin for the diagnosis of respiratory bacterial infections in the elderly is high.

关 键 词：呼吸道细菌性感染 非细菌性感染 诊断效果 降钙素原 白细胞介素6 内毒素 

分 类 号：R446.11[医药卫生—诊断学]