点阵射频联合外用重组人碱性成纤维细胞生长因子治疗玫瑰痤疮的临床研究  

fiDot-matrix radiofrequency combined with external recombinant human basic fibroblast growth factor for treatment of facial rosacea

作　　者：樊玉[1] 陈婧弘 刘娟[1] 杨哲 FAN Yu;CHEN Jinghong;LIU Juan;YANG Zhe(Department of Dermatology,Nanyang First People's Hospital,Henan Province,473000,China)

机构地区：[1]南阳市第一人民医院皮肤科,河南南阳473000

出　　处：《中国医疗美容》2024年第11期12-15,共4页China Medical Cosmetology

摘　　要：目的探讨点阵射频联合外用重组人碱性成纤维细胞生长因子(rh-bFGF)治疗玫瑰痤疮临床观察。方法回顾性分析2021年2月至2024年1月南阳市第一人民医院收治的99例面部玫瑰痤疮患者,按治疗方法不同分为两组。对照组45例,采用点阵射频治疗,观察组44例,采用点阵射频联合外用rh-bFGF治疗。结果观察组患者治疗总有效率高于对照组;治疗后的各项皮损症状评分均低于对照组,痤疮特异性生活质量量表(Acne-QOL)内各维度评分均高于对照组,上述差异均有统计学差异(P<0.05);两组患者不良反应比较,差异无统计学意义(P>0.05)。结论点阵射频联合外用rh-bFGF可减轻玫瑰痤疮患者皮损症状,提高生活质量,无严重不良反应。Objective To analyze the effects of radiofrequency lattice combined with external recombinant human basic fifibroblast growth factor(rh-bFGF)on facial rosacea patients.Methods A total of 99 patients with facial rosacea admitted to Nanyang fifirst people's Hospital from February 2021 to January 2024 were retrospectively analyzed.They were divided into two groups according to different treatment methods.45 cases in the control group were treated with dot matrix radiofrequency,and 44 cases in the observation group were treated with dot matrix radiofrequency combined with topical RH bFGF.Results The total effective rate of the observation group was higher than that of the control group;After treatment,the scores of skin lesion symptoms in the treatment group were lower than those in the control group,and the scores of all dimensions in acne specifific quality of life scale(acne QOL)were higher than those in the control group,and the above differences were statistically signifificant(P<0.05);There was no signifificant difference in adverse reactions between the two groups(P>0.05).Conclusions rh-bFGF combined with dot-matrix radiofrequency can alleviate skin lesions and improve quality of life in rosacea patients without serious adverse reactions.

关 键 词：面部玫瑰痤疮 点阵射频 重组人碱性成纤维细胞生长因子 不良反应 

分 类 号：R758.734[医药卫生—皮肤病学与性病学]