Correlation analysis between urinary crystals and upper urinary calculi  

作　　者：Xi Zhang Yang Zheng Yichun Wang Xiyi Wei Shuai Wang Jie Zheng Jixiang Yao Chen Xu Zhijun Cao Chao Qin Lujiang Yi Ninghong Song 

机构地区：[1]Department of Urology,the First Affiliated Hospital of Nanjing Medical University,Nanjing,China [2]Nanjing Hospital of Traditional Chinese Medicine,Nanjing Hospital of Chinese Medicine,Nanjing,China [3]Department of Urology,Wuhu Hospital Affiliated to East China Normal University,Wuhu,China [4]Department of Urology,Suzhou Ninth People's Hospital,Soochow University,Suzhou,China [5]Department of Laboratory,the First Affiliated Hospital of Nanjing Medical University,Nanjing,China

出　　处：《Asian Journal of Urology》2024年第4期596-603,共8页亚洲泌尿外科杂志（英文）

基　　金：supported by the National Natural Science Foundation of China(No.82071638 to Song N).

摘　　要：Objective:This study aimed to analyze the correlation between urinary crystals and urinary calculi.Methods:Clinical data, including urinary crystal types, were collected from 237 patients with urinary calculi. The detection rate of urine crystals and their correlation with stone composition were analyzed. The receiver operating characteristic curve analysis was used to determine the best cut-off value for predicting stone formation risk based on calcium oxalate crystals in urine.Results:Calcium oxalate was the most common component in 237 patients. Among them, 201 (84.81%) patients had stones containing calcium oxalate. In these patients, calcium oxalate crystals were detected in 45.77% (92/201) of cases. In different groups of calcium oxalate stones, calcium oxalate crystals accounted for more than 90% of the total number of crystals detected in each group. The detection rate of calcium oxalate crystals was higher in first-time stone formers than in recurrent patients. The receiver operating characteristic curve analysis suggested a cut-off value of 110 crystals/μL for predicting stone formation, validated with 65 patients and 100 normal people.Conclusion:Calcium oxalate crystals in urine can predict the composition of calcium oxalate stones and indicate a higher risk of stone formation when the number exceeds 110 crystals/μL. This non-invasive method may guide clinical treatment and prevention strategies.

关 键 词：CALCULUS Urine crystal Calcium oxalate crystal Predict model 

分 类 号：R699[医药卫生—泌尿科学]