1型神经纤维瘤病性脊柱侧凸矫形术中椎弓根螺钉置钉安全性研究进展  

Research progress on pedicle screw placement safety in orthopedic treatment of type 1 neurofibromatosis scoliosis

作　　者：王文博 汤三泉 李国军 陈焕雄 WANG Wenbo;TANG Sanquan;LI Guojun;CHEN Huanxiong(Department of Spinal Surgery,First Affiliated Hospital,Hainan Medical University,Haikou,Hainan 570100,China)

机构地区：[1]海南医学院第一附属医院脊柱外科,海南海口570100

出　　处：《重庆医学》2024年第23期3633-3638,3644,共7页Chongqing Medical Journal

基　　金：国家自然科学基金项目(81902270)。

摘　　要：神经纤维瘤病(NF)作为一种常染色体显性遗传疾病,常累及全身多个系统,分为1型与2型NF。神经纤维瘤病性脊柱侧凸(NFS)主要为1型,1型神经纤维瘤病性脊柱侧凸(NF1-S)在脊柱解剖学及形态学上表现为顶椎旋转和椎弓根形态异常,导致侧凸矫形术中椎弓根螺钉置入难度与风险极大。为提高手术安全性,该文深入探讨NF1-S患者的椎弓根形态学及解剖学结构,分析不同椎弓根螺钉辅助置入技术的精确性和安全性,为临床手术提供参考,促进治疗水平提升。Neurofibromatosis(NF)as an autosomal dominant disease usually involves multiple systems throughout the body and is classified as type 1 or type 2 NF.Neurofibromatosis scoliosis(NFS)is mainly type 1,and severe neurofibromatosis scoliosis type 1(NF1-S)is manifested by abnormalities in spinal anatomy and morphology,such as rotation of the parietal vertebrae and abnormal morphology of the pedicles,which leads to the difficulty and maximal risk of pedicle screw placement in scoliosis orthopedic surgery.In order to improve the safety of surgery,this paper discusses the morphology and anatomical structure of the pedicles in the patients with NF1-S,and analyzes the accuracy and safety of different pedicle-assisted screw placement techniques to provide reference for clinical surgery and promote the improvement of treatment level.

关 键 词：1型神经纤维瘤病性脊柱侧凸 椎弓根异常 术中计算机导航 3D超声 3D打印导板 

分 类 号：R687.3[医药卫生—骨科学]