Practical steps to develop a transcriptomic test for blood doping  

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作  者:Shaun Sutehall Fernanda Malinsky Sven Voss Neil Chester Xiao Xu Yannis Pitsiladis 

机构地区:[1]Clincial Research Division,Alder Hey Children’s NHS Foundation Trust,Liverpool,UK [2]Research Institute for Sport and Exercise Sciences,Liverpool John Moores University,Liverpool,UK [3]Department of Sport and Health Sciences,Hong Kong Baptist University,Hong Kong,China [4]Institute of Doping Analysis and Sport Biochemistry,Kreischa,Germany [5]MGI Tech,Shenzhen,China

出  处:《Translational Exercise Biomedicine》2024年第2期105-110,共6页运动转化生物医学(英文)

摘  要:Blood doping remains a significant problem that threatensthe integrity ofsport.The currentindirect method for detecting blood doping involves the longitudinal measurement of an athlete’s haematological variables and identification of suspicious results that are indicative of doping(i.e.,the athlete biological passport).While this has played a significant role in the protection of clean sport,improvements are needed.The development of a transcriptomic test,that can be used to detect the use of blood doping has been discussed and researched for decades and yet,an anti-doping test that can be adopted by the World Anti-Doping Agency(WADA)is yet to be established.With recent advancements in our understanding,as well as in methods of sample collection,the possibility of a transcriptomic test that can be used by WADA,is imminent.There are,however,several practical considerations that mustfirst be made,that will be highlighted in this perspective article.

关 键 词:ANTI-DOPING testing blood doping EPO TRANSCRIPTOMICS 

分 类 号:G81[文化科学—体育学]

 

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