Structural insights of poly(butylene adipate-co-terephthalate)depolymerases  

作　　者：Yu Yang Zhongrui Wang Yingyu Zheng Shujing Cheng Chun-Chi Chen ReyTing Guo 

机构地区：[1]State Key Laboratory of Biocatalysis and Enzyme Engineering,Hubei Hongshan Laboratory,Hubei Collaborative Innovation Center for Green Transformation of BioResources,Hubei Key Laboratory of Industrial Biotechnology,School of Life Sciences,Hubei University,Wuhan,430062,People's Republic of China [2]Department of Immunology and Pathogen Biology,School of Basic Medical Sciences,Hangzhou Normal University,Hangzhou,311121,People's Republic of China

出　　处：《Advanced Agrochem》2024年第2期126-132,共7页现代农业化学（英文）

基　　金：supported by the National Key Research and Devel-opment Program of China(2021YFC2104000);Hubei Hongshan Laboratory(2022hszd030);the National Natural Science Foundation of China(32271318).

摘　　要：Poly(butylene adipate-co-terephthalate),PBAT,is one of the most popular plastics nowadays and is becoming a large burden to the environment when PBAT waste is accumulated.Biodegradation of PBAT is an environmentally friendly method to treat PBAT waste.In the past two decades,a couple of microbial strains or mixed strains have been chemically characterized.From this,many PBAT depolymerases have been isolated and further structurally determined.The review we focused on the PBAT depolymerases that have been structurally characterized,including lipases,esterases,and cutinases.We also discussed which shape of the substrate-binding tunnels is beneficial for recognizing and decomposing polymer chains of PBAT,which would be important guidance in directing the designation of PBAT depolymerases.

关 键 词：BIODEGRADATION PBAT Crystal structure DEPOLYMERASE Substrate-binding tunnel 

分 类 号：TQ3[化学工程]