Spray-induced gene silencing in phytopathogen:Mechanisms,applications,and progress  

作　　者：Li He Yifan Zhou Qin Mo Yanna Huang Xueming Tang 

机构地区：[1]School of Agriculture and Biology,Shanghai Jiao Tong University,Shanghai,China [2]Key Laboratory of Urban Agriculture,Ministry of Agriculture and Rural Affairs,Shanghai,China [3]Shanghai Yangtze River Delta Eco-Environmental Change and Management Observation and Research Station,Ministry of Science and Technology,Ministry of Education,Shanghai,China [4]Silicon Gene Technologies(Shanghai)Co.,Ltd.,Shanghai,China

出　　处：《Advanced Agrochem》2024年第4期289-297,共9页现代农业化学（英文）

基　　金：supported by the National Key Research and Development Program of China(2023YFD1700700);Shanghai Agricultural Science and Technology Innovation Project(K2023018);the Shanghai Jiaotong University Talent Foundation(No.WH221615001),and Program for Shanghai Leading Talent.

摘　　要：Phytopathogens can continuously cause serious losses worldwide to crop,fruit,and vegetable yields.The excessive use of conventional fungicides in pathogen management has raised severe environmental and health side effects and induced fungicide-resistant pathogen strains.RNA-based spray-induced gene silencing(SIGS)has emerged as an ecologically sustainable pathogen control approach.Here,we introduce the SIGS mechanism in plant pathogens,summarize the application of SIGS in controlling plant pathogens,and highlight the major considerations of SIGS.In addition,we propose the future perspectives of SIGS in crop protection and disease management.

关 键 词：PATHOGEN SIGS dsRNA uptake dsRNA stability Nanoparticles dsRNA production Risk assessment Regulatory framework 

分 类 号：S43[农业科学—农业昆虫与害虫防治]