A smart dual-responsive nanoplatform for delivery of prochloraz for the control of rice blast disease  

作　　者：Zhaoyang Zhang Donglin Li Chang Yu Jiaqing Li Dan Sun Jiayin Wang Mohamed Mmby Jianhong Li Hong You Shun He 

机构地区：[1]The Center of Crop Nanobiotechnology,College of Plant Science and Technology,Huazhong Agricultural University,No.1 Shizishan Street,Wuhan,430074,China

出　　处：《Advanced Agrochem》2024年第4期328-336,共9页现代农业化学（英文）

基　　金：supported by the National Key Research and Development Program of China(2022YFA1207400);National Natural Science Foundation of China(32272579,31972302);Knowledge Innovation Program of Wuhan-Shuguang Project(2022020801020235);First Class Discipline Construction Funds of College of Plant Science and Technology,Huazhong Agricultural University(2022ZKPY005);Fundamental Research Funds for the Central Universities(2662022ZKYJ002 and 2662022YJ015).

摘　　要：Nano-controlled release formulations present a promising strategy to mitigate pesticide losses and enhance efficiency.In this study,a pH and GSH-responsive nanoplatform using mesoporous organosilica nanoparticles(MONs)as a carrier and poly(tannic acid)(PTA)as capping agent was established for controlling prochloraz(Pro)release.The obtained Pro@MON@PTA was characterized by transmission electron microscopy(TEM),scanning electron microscopy(SEM),Fourier transform infrared spectroscopy(FTIR),thermogravimetric analysis(TGA).The results indicate the successful preparation of Pro@MON@PTA nanoparticles,featuring uniform particle size(190 nm),excellent dispersibility,and a prochloraz loading efficiency of 17.2%.Evaluation of contact angle and adhesion work demonstrated superior adhesion of MON@PTA to rice leaves compared to MON.Controlled release studies revealed dual-responsive release properties of Pro@MON@PTA to acid and GSH.Additionally,photostability testing indicated effective ultraviolet light shielding by the carrier,reducing prochloraz degradation under irradiation.Bioassay results indicated equivalent fungicidal activity against Magnaporthe oryzae between Pro@MON@PTA and prochloraz technical and prochloraz EW after a 7-day treatment.However,in vivo experiments demonstrated that Pro@MON@PTA exhibited superior control efficacy compared to prochloraz EW.These findings suggested that MON@PTA holds significant potential for plant disease management.

关 键 词：PROCHLORAZ Mesoporous organosilica nanoparticles Controlled-released formulation Magnaporthe oryzae Biological activity 

分 类 号：S51[农业科学—作物学]