TWIP-assisted Zr alloys for medical applications:Design strategy,mechanical properties and first biocompatibility assessment  

作　　者：Junhui Tang Hongtao Yang Bingnan Qian Yufeng Zheng Philippe Vermaut Frédéric Prima Fan Sun 

机构地区：[1]Chimie ParisTech,CNRS-UMR8247,Institut de Recherche de Chimie Paris,PSL Research University,Paris 75005,France [2]School of Materials Science and Engineering,Peking University,Beijing 100871,China [3]School of Engineering Medicine,Beihang University,Beijing 100191,China [4]Department of Mechanical and Energy Engineering,Southern University of Science and Technology,Shenzhen 518055,China [5]Sorbonne University,UPMC University Paris,UFR926,Paris 75005,France

出　　处：《Journal of Materials Science & Technology》2024年第17期32-42,共11页材料科学技术（英文版）

基　　金：the support of the French Agence Nationale de la Recherche(ANR),under grant ANR-21-CE08-0022(project ISANAMI);Junhui TANG is sponsored by the China Scholarship Council.

摘　　要：This study proposes a novel strategy for the design of a new family of metastable Zr alloys.These al-loys offer improved mechanical properties for implants,particularly in applications where conventional stainless steels and Co-Cr alloys are currently used but lack suitability.The design approach is based on the controlled twinning-induced plasticity(TWIP)effect,significantly enhancing the ductility and strain-hardenability of the Zr alloys.In order to draw a“blueprint”for the compositional design of biomedical T WIP(Bio-T WIP)Zr alloys-using only non-toxic elements,the study combines D-electron phase stability calculations(specifically bond order(Bo)and mean d-orbital energy(Md))with a systematic experimental screening of active deformation mechanisms within the Zr-Nb-Sn alloy system.This research aids in ac-curately identifying the TWIP line,which signifies the mechanism shift between TWIP and classic slip as the primary deformation mechanism.To demonstrate the efficacy of the TWIP mechanism in enhancing mechanical properties,Zr-12Nb-2Sn,Zr-13Nb-1Sn,and Zr-14Nb-3Sn alloys are selected.Results indicate that the TWIP mechanism leads to a significant improvement of strain-hardening rate and a uniform elongation of∼20%in Zr-12Nb-2Sn,which displays both{332}<113>mechanical twinning and disloca-tion slip as the primary deformation mechanisms.Conversely,Zr-14Nb-3Sn exhibits the typical mechan-ical properties found in stable body-centered cubic(BCC)alloys,characterized by the sole occurrence of dislocation slip.Cell viability tests confirm the superior biocompatibility of Zr-Nb-based alloys with deformation twins on the surface,in line with existing literature.Based on the whole set of results,a comprehensive design diagram is proposed.

关 键 词：Zr alloys STRAIN-HARDENING Twinning-induced plasticity(TWIP) Bo-Md diagram BIOCOMPATIBILITY Biomedical materials 

分 类 号：TG146.23[一般工业技术—材料科学与工程] R783.1[金属学及工艺—金属材料]