Hirschsprung disease:common and uncommon variants  

作　　者：Lily S Cheng Richard J Wood 

机构地区：[1]Department of Surgery,Division of Pediatric Surgery,University of Virginia,Charlottesville,Virginia,USA [2]Department of Pediatric Colorectal and Pelvic Reconstructive Surgery,Nationwide Children's Hospital,Columbus,Ohio,USA

出　　处：《World Journal of Pediatric Surgery》2024年第3期233-236,共4页世界小儿外科杂志（英文）

基　　金：the National Institute of Diabetes and Digestive and Kidney Diseases(Grant number:K08DK133673).

摘　　要：OVERVIEW OF SHORT-SEGMENT HIRSCHSPRUNG DISEASE The most common variant of Hirschsprung disease(HSCR)is short-segment or recto-sigmoid disease.The majority(70%-85%)of HSCR is limited to the rectum or sigmoid colon.1 These patients usually present in the neonatal period with'typical'signs and symp-toms:failure to pass meconium within the first 24-48 hours,abdominal distention,vomiting,explosive passage of stool/gas,and failure to thrive.12 Patients may also present with signs and symptoms of Hirschsprung-associated enterocolitis(HAEC),which include abdom-inal tenderness,fever,explosive diarrhea,and bloody stools.3 Rectal irrigation is usually an effective first-line management strategy in patients with short-segment HSCR and is the mainstay of treatment for HAEC.

关 键 词：STOOL DIARRHEA COLON 

分 类 号：R726.5[医药卫生—儿科]