基于数据挖掘技术探讨藤类中药在皮肤病中的应用  

Using data mining technology to summarize the application of rattan drugs in dermatosis

作　　者：刘茜玮 于鸿妲 吴豆豆 刘家邑 蔡锐 代博文 白彦萍[2] LIU Qiamei;YU Hongda;WU Doudou;LIU Jiayi;CAI Rui;DAI Bowen;BAI Yanping(Beijing University of Chinese Medicine,Beijing 100029,China;Department of Dermatology,China-lapan Friencship Hospial,Beijing 100290,China)

机构地区：[1]北京中医药大学,北京100029 [2]中日友好医院皮肤科,北京100029

出　　处：《中药与临床》2024年第6期42-46,53,共6页Pharmacy and Clinics of Chinese Materia Medica

基　　金：国家自然科学基金面上项目(82074445);国家中医药管理局第六批全国老中医药专家学术经验继承项目(国中医药人教发[2017]29号);2023年北京中医药大学研究生自主科研课题(ZJKT2023113)。

摘　　要：目的:通过数据挖掘技术总结归纳藤类中药在皮肤病中的应用特点及用药规律,更好的指导临床用药。方法:研究整理归纳了《中医方剂大辞典》《中华医典》中含有藤类中药治疗皮肤病的方剂,之后运用“中医辅助传承平台V3.0”软件对资料中的疾病种类、药物频数、用药特点及组方规律等进行分析。结果:共筛选出符合条件的方剂939首,涉及到皮肤病196种,出现频率最高的前5位分别是痘6.79%、痘疮4.84%、疹4.03%、痈疽4.03%、痘疹3.90%,涉及到藤类中药50种,使用频率最高的前5位藤类中药依次为木通5.95%、忍冬藤0.60%、钩藤0.56%、海风藤0.44%、紫金藤0.13%。置信度较高的关联规则包括“防风-木通”、“当归-木通”、“连翘-木通”等;潜在的药物组合包括“木通-甘草-当归-连翘-防风-黄芩”等。结论:通过本研究对藤类中药在皮肤病方面的应用及组方规律有了较为清晰的认识,对中医治疗皮肤病临床用药有一定指导意义。Objective: To summarize the application characteristics and medication rules of rattan drugs in dermatosis through data mining technology to guide clinical medication better. Methods: The research sorted out and summarized the prescriptions containing rattan drugs for the treatment of dermatosis in the dictionary of traditional Chinese medicine prescriptions and the Chinese medical dictionary.Then, the disease types, drug frequency, medication characteristics and prescription rules in the data were analyzed using the software of“traditional Chinese medicine auxiliary inheritance platform V3.0”. Results: A total of 939 qualified prescriptions were selected,involving 196 kinds of dermatosis. The top five with the highest frequency were Dou 6.79%, Douchuang 4.84%, Zhen 4.03%, Yongju 4.03% and Douzhen 3.90% respectively, involving 50 kinds of rattan drugs. The top five rattan drugs with the highest frequency were Mutong 5.95%, Rendongteng 0.60%, Gouteng 0.56%, Haifengteng 0.44% and Zijinteng 0.13%. Association rules with high confidence included“Fangfeng-Mutong”,“Danggui-Mutong”,“Lianqiao-Mutong”, etc. Potential drug combinations included“MutongGancao-Danggui-Lianqiao-Fangfeng-Huangqin”, etc. Conclusion: Through this study, we have a better understanding of the application and formula law of rattan drugs in dermatosis. For a clear understanding, it has certain guiding significance for the clinical medication of traditional Chinese medicine in the treatment of dermatosis.

关 键 词：数据挖掘 藤类中药 皮肤病 

分 类 号：R275[医药卫生—中医皮科]