从代谢重编程探讨甲状腺结节气滞痰阻证病机  

Exploring the Pathogenesis of Thyroid Nodules with Qi Stagnation and Phlegm Obstruction Syndrome from the Perspective of Metabolic Reprogramming

作　　者：史佩玉 刘旭菲 魏畅 布天杰 温志歌 张玉人[1] 倪青[1] SHI Pei-yu;LIU Xu-fei;WEI Chang;BU Tian-jie;WEN Zhi-ge;ZHANG Yu-ren;NI Qing(Department of Endocrinology,Guang'anmen Hospital,China Academy of Chinese Medical Sciences,Beijing,100053)

机构地区：[1]中国中医科学院广安门医院内分泌科,北京100053

出　　处：《中国中西医结合杂志》2024年第11期1386-1390,共5页Chinese Journal of Integrated Traditional and Western Medicine

基　　金：北京市中医药科技发展资金项目(No.JCZX-2020-08);中国中医科学院科技创新工程项目(No.CI2021A01610)。

摘　　要：甲状腺结节是临床常见的内分泌系统疾病,甲状腺是人体能量代谢的重要器官,在调节机体稳态中发挥着重要作用。代谢重编程构建的能量代谢新模式为甲状腺结节的发生和发展提供物质基础与能量动力,贯穿疾病发生发展始终,与气滞痰阻证物质能量利用障碍、病理产物堆积的基本特点不谋而合。以理气化痰散结法作为甲状腺结节气滞痰阻证基本治法,或可重塑代谢重编程,维系物质与能量稳态。Thyroid nodule,a common endocrine system disease,is often clinically seen.The thyroid gland is an important organ for energy metabolism in the human body and plays a crucial role in regulating body homeostasis.The new mode of energy metabolism constructed by metabolism reprogramming provided the material bases and energy power for the occurrence and development of thyroid nodules,which run through its entire process and coincided with the basic characteristics of qi stagnation and phlegm obstruction(obstacles in the utilization of materials energy and accumulation of pathological products).Using qi regulating,phlegm resolving,and nodules dissipating method as the basic treatment for qi stagnation and phlegm obstruction in thyroid nodules might reshape metabolic reprogramming and maintain materials and energy homeostasis.

关 键 词：甲状腺结节 代谢重编程 气滞痰阻 理气化痰散结 中西医结合 

分 类 号：R259[医药卫生—中西医结合]