基于“毒、虚、瘀”探讨脓毒症血管内皮细胞损伤与微循环障碍  

Investigation of Vascular Endothelial Cell Injury and Microcirculation Disturbance in Sepsis Based on"Toxicity,Deficiency and Stasis"

作　　者：金力 何健卓[1,2] 尹鑫[1,2] 郭力恒[1,2] JIN Li;HE Jian-zhuo;YIN Xin;GUO Li-heng(The Second Clinical Medical School of Guangzhou University of Chinese Medicine,Guangzhou,510405;Department of Intensive Care Medicine,Guangdong Hospital of Traditional Chinese Medicine,Guangzhou,510120)

机构地区：[1]广州中医药大学第二临床医学院,广州510405 [2]广东省中医院重症医学科,广州510120

出　　处：《中国中西医结合杂志》2024年第11期1391-1395,共5页Chinese Journal of Integrated Traditional and Western Medicine

基　　金：国家自然科学基金资助项目(No.82074216);广东省中医院名中医药专家学术经验传承工作室建设项目(No.中医二院[2014]89号)。

摘　　要：脓毒症过度炎症导致的内皮细胞损伤,是发生脓毒症微循环障碍的关键病理机制。笔者结合中医学“毒、虚、瘀”理论和现代病理机制,探讨脓毒症内皮细胞损伤导致微循环障碍的致病机制,旨在为中西医治疗脓毒症提供更多思路与理论支持。Endothelial cell damage caused by excessive inflammation in sepsis is the key pathological mechanism of microcirculation disturbance in sepsis.This article combined the theory of"Toxicity,Deficiency and Stasis"of Chinese medicine and modern pathological mechanism to explore the pathogenic mechanism of microcirculation disturbance caused by endothelial cell injury in sepsis,aiming to provide more ideas and theoretical support for the treatment of sepsis with integrated Chinese and Western medicine.

关 键 词：脓毒症 内皮细胞损伤 微循环障碍 中医学理论 中西医结合 

分 类 号：R459.7[医药卫生—急诊医学]