窄带CE-Chirp ASSR在听障儿童听阈评估中的应用  

Application of narrow-band CE-Chirp NB ASSR in hearing threshold assessment of hearing-impaired children

作　　者：周佳蕾 陈芳 李晓艳[1] ZHOU Jialei;CHEN Fang;LI Xiaoyan(Shanghai Children's Hospital,Ear,Nose,Throat,Head and Neck Surgery Department of Shanghai Jiao Tong University School of Medicine Affiliated Children's Hospital,Shanghai,200062,China)

机构地区：[1]上海市儿童医院,上海交通大学医学院附属儿童医院耳鼻咽喉头颈外科,上海200062

出　　处：《临床耳鼻咽喉头颈外科杂志》2024年第11期1012-1016,共5页Journal of Clinical Otorhinolaryngology Head And Neck Surgery

基　　金：上海交通大学“交大之星”计划重点项目(No:YG2023ZD23)。

摘　　要：目的:探讨窄带CE-Chirp声听觉稳态反应(NB CE-Chirp ASSR)测试在听障儿童听阈评估中的应用价值。方法:回顾性研究2023年1月至2023年12月在上海市儿童医院确诊的感音神经性听力损失患儿44例(88耳)的听力检测结果,其中听力损失轻度组19耳,中度组26耳,重度组20耳,极重度组23耳。分析不同听力损失组听性脑干反应(ABR)阈值、纯音测听(PTA)阈值与NB CE-Chirp ASSR反应阈之间的相关性。结果:不同程度的听力损失组其ABR与NB CE-Chirp ASSR(2 000~4 000 Hz)反应阈差值为0.50~4.08 dB;每组NB CE-Chirp ASSR与ABR反应阈之间均有显著相关性(P<0.001),且轻度、重度及极重度组的相关系数均>0.8,呈极强相关。各组PTA与NB CE-Chirp ASSR平均阈值差值为1.88~3.91 dB;相关系数均>0.8,呈极强相关。每组在500、1 000、2 000、4 000 Hz处PTA与NB CE-Chirp ASSR反应阈差值为0.25~3.84 dB;随频率升高,PTA与NB CE-Chirp ASSR反应阈二者间的相关系数呈上升趋势,系数最高的频率为4 000 Hz,r均>0.9,其次为2 000 Hz,500 Hz处相对较低;在极重度组中各频率系数均大于0.7,呈极强相关。结论:NB CE-Chirp ASSR具备良好的频率特异性,能可靠地评估听障儿童的听觉阈值。Objective:To investigate the application value of NB CE-Chirp ASSR in the assessment of hearing threshold in children with hearing impairment.Methods:The hearing test results of 44 children with sensorineural hearing loss(88 ears) diagnosed in Shanghai Children's Hospital from January 2023 to December 2023 were retrospectively studied,including 19 ears in mild hearing loss group,26 ears in moderate group,20 ears in severe group and 23 ears in extremely severe group.Correlations between auditory brainstem response(ABR) thresholds,pure tone audiometry(PTA) thresholds and NB CE-Chirp ASSR response thresholds in different hearing loss groups were analyzed.Results:The threshold difference between ABR and NB CE-Chirp ASSR(2 000-4 000 Hz) was between 0.50-4.08 dB in different degrees of hearing loss group.There was a significant correlation between NB CE-Chirp ASSR and ABR response threshold in each group(P<0.001),and the correlation coefficients of mild,severe and extremely severe groups were all greater than 0.8,showing a strong correlation.The average threshold difference between PTA and NB CE-Chirp ASSR in each group was between 1.88-3.91 dB.The correlation coefficients were all greater than 0.8,showing a strong correlation.The difference between PTA and NB CE-Chirp ASSR response threshold at 500,1 000,2 000 and 4 000 Hz in each groupwas between 0.25-3.84 dB.With the increase of frequency,the correlation coefficient between PTA and NB CE-Chirp ASSR response threshold showed an upward trend.The frequency with the highest coefficient was 4 000 Hz,and the r values were all greater than 0.9,followed by 2 000 Hz,and the correlation coefficient was relatively low at 500 Hz.In the extremely severe group,each frequency coefficient was greater than 0.7,showing a strong correlation.Conclusion:NB CE-Chirp ASSR has good frequency specificity and can reliably assess hearing thresholds in hearing-impaired children.

关 键 词：窄带CE-Chirp声 听觉稳态反应 听性脑干反应 纯音听阈 儿童 听力障碍 

分 类 号：R764.5[医药卫生—耳鼻咽喉科]