突发性聋预后疗效判定标准研究  

Research on the prognosis and efficacy criteria of sudden sensorineural hearing loss

作　　者：单长硕 王大勇 王秋菊 SHAN Changshuo;WANG Dayong;WANG Qiuju(Department of Audio-Vestibular Medicine,Senior Department of Otolaryngology-Head and Neck Surgery,the Sixth Medical Center of Chinese PLA General Hospital,Institute of Otolaryngology,Beijing,100048,China;Binzhou Medical University;National Clinical Research Center for Otolaryngologic Diseases,Ministry of Education Chinese PLA Institute of Otolaryngology)

机构地区：[1]中国人民解放军总医院第六医学中心耳鼻咽喉头颈外科,医学部耳鼻咽喉内科,耳鼻咽喉研究所 [2]滨州医学院 [3]国家耳鼻咽喉疾病临床医学研究中心

出　　处：《临床耳鼻咽喉头颈外科杂志》2024年第11期1085-1090,共6页Journal of Clinical Otorhinolaryngology Head And Neck Surgery

基　　金：国家重点研发计划(No:2023YFC2508400、2023YFC2509800);国家自然科学基金面上项目(No:82171130)。

摘　　要：突发性聋是一种常见病、多发病。纵览国内外突发性聋诊治的疗效评估,各国在治疗疗效评估指标和标准方面各具特色,常用疗效判定的指标包括:(1)平均听阈;(2)受损频率听力提高的绝对值;(3)平均听阈提升的百分比;(4)言语识别率;(5)言语识别阈等。评估标准多以疗效分级或平均听阈的改善水平作为治疗有效的判定标准,缺乏统一标准,不利于全球突发性聋相关研究的同质化推进。本文系统回顾了多国突发性聋临床实践指南及质量较高的临床多中心研究中的疗效评估指标和标准,以便为我国突发性聋诊治效果评价改进提供参考。Sudden sensorineural hearing loss is a common and frequently-occurring disease.Looking at the efficacy evaluation of the diagnosis and treatment of sudden sensorineural hearing loss at home and abroad,each country has its own characteristics in the indicators and criteria of the treatment efficacy evaluation,and the common indicators of efficacy evaluation include:average pure-tone hearing threshold,the absolute value of hearing improvement of impaired frequency,the percentage of average pure-tone hearing threshold increase,speech discrimination score,speech recognition threshold,etc.The evaluation criteria mostly take the efficacy grade or the improvement level of average hearing threshold as the criterion of effective treatment,and the lack of unified standards is not conducive to the homogenization of global research related to sudden sensorineural hearing loss.In order to provide reference for the clinical evaluation of sudden sensorineural hearing loss in China,this study systematically reviewed the clinical practice guidelines and the evaluation indexes and criteria of clinical efficacy in high quality clinical multicenter studies of the disease in many countries.

关 键 词：突发性聋 疗效判定 指标 标准 

分 类 号：R764.43[医药卫生—耳鼻咽喉科]