Effects of needling at Sanyinjiao(SP6)acupuncture point on blood glucose levels and cardiovascular functions in patients with type 2 diabetes mellitus:a randomized placebo-controlled study  

三阴交穴位针刺对2型糖尿病患者血糖水平和心血管功能的影响:一项随机安慰剂对照研究

作　　者：S.Priyadharshini A.Mooventhan Venkatalakshmi Saravanan N.Mangaiarkarasi 

机构地区：[1]Department of Acupuncture and Energy Medicine,Government Yoga and Naturopathy Medical College,Chennai,Tamilnadu 600106,India [2]Department of Research,Government Yoga and Naturopathy Medical College,Chennai,Tamilnadu 600106,India

出　　处：《Digital Chinese Medicine》2024年第3期224-230,共7页数字中医药（英文）

摘　　要：Objective To determine the effect of needling at Sanyinjiao(SP6)on random blood glucose(RBG)levels and cardiovascular function in patients with type 2 diabetes mellitus(T2DM).Methods In this randomized placebo-controlled study,T2DM patients(aged 35-65 years)were recruited from the Government Yoga and Naturopathy Medical College and Hospital,Chennai,India,between January 5,2022 and March 15,2023.Participants were randomly as-signed to either acupuncture group or sham acupuncture group.The acupuncture group re-ceived bilateral needling at Sanyinjiao(SP6)while sham acupuncture group received needling at a non-acupuncture point[1.5 cun lateral to Sanyinjiao(SP6)]for 30 min.Primary outcome was RBG,and secondary outcomes included systolic blood pressure(SBP),diastolic blood pressure(DBP),pulse rate(PR),pulse pressure(PP),mean arterial pressure(MAP),rate pressure product(RPP),and double product(Do-P).All parameters were assessed imme-diately before and after intervention.Results A total of 100 patients with T2DM were enrolled in the study,and blinded to acupuncture group(n=50)and sham acupuncture group(n=50).Intergroup analysis showed that significant reductions in RBG(P<0.001),SBP(P=0.035),DBP(P=0.008),and MAP(P=0.009)were found in acupuncture group compared with sham acupuncture group.Within-group analysis showed significant reductions in RBG(P<0.001),SBP(P<0.001),DBP(P=0.008),PP(P=0.023),MAP(P<0.001),RPP(P<0.001),and Do-P(P=0.002)in acupunc-ture group,whereas sham acupuncture group showed a significant decrease in PR(P=0.023)only in the post-test assessment compared with pre-test assessment.Conclusion A period of 30 min of needling at the Sanyinjiao(SP6)acupuncture point re-duces RBG and promotes cardiovascular function in patients with T2DM as compared with needling at non-acupuncture points.Sanyinjiao(SP6)acupuncture may offer an immediate,non-pharmacological intervention to strengthen glycemic control management and cardio-vascular health in T2DM patients.目的本研究旨在确定三阴交(SP6)穴位针刺对2型糖尿病患者(T2DM)随机血糖(RBG)水平和心血管功能的影响。方法在这项随机安慰剂对照研究中,期间从印度金奈政府瑜伽和自然疗法医学院和医院招募T2DM患者(年龄35−65岁),时间跨度为2022年1月5日至2023年3月15日。参与者被随机分配到针灸组或假针灸组。针灸组接受双侧三阴交(SP6)穴位针刺,而假针灸组接受非穴位点(距三阴交侧位1.5寸处)针刺,每次30分钟。主要观察指标为RBG,次要观察指标包括收缩压(SBP)、舒张压(DBP)、脉搏率(PR)、脉压(PP)、平均动脉压(MAP)、心率血压乘积(RPP)和心率血压双乘积(Do-P)。所有参数在干预前后立即进行评估。结果共有100名T2DM患者参与研究,被随机分配至针灸组(n=50)和假针灸组(n=50)。组间分析显示,针灸组与假针灸组相比,RBG(P<0.001)、SBP(P=0.035)、DBP(P=0.008)和MAP(P=0.009)显著降低。组内分析显示,针灸组RBG(P<0.001)、SBP(P<0.001)、DBP(P=0.008)、PP(P=0.023)、MAP(P<0.001)、RPP(P<0.001)和Do-P(P=0.002)显著降低,而假针灸组仅在脉搏率(PR)上表现出显著降低(P=0.023)。结论与非穴位点针刺相比,30分钟的三阴交(SP6)穴位针刺可以降低T2DM患者的RBG并改善其心血管功能。三阴交(SP6)穴位针刺可能作为一种即时、非药物干预手段,加强T2DM患者的血糖控制管理和促进心血管健康。

关 键 词：ACUPUNCTURE Diabetes Sanyinjiao(SP6) Type 2 diabetes mellitus(T2DM) Blood glucose 

分 类 号：R246.1[医药卫生—针灸推拿学]