五加属植物资源与次生代谢物的研究进展  

Resources and secondary metabolites from Eleutherococcus plants:a review

作　　者：王成霖 薛哲勇 刘娟[2] 华欣 WANG Cheng-lin;XUE Zhe-yong;LIU Juan;HUA Xin(College of Life Sciences,Northeast Forestry University,Harbin 150006,China;State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs,National Resource Center for Chinese Materia Medica,China Academy of Chinese Medical Sciences,Beijing 100700,China)

机构地区：[1]东北林业大学生命科学学院,黑龙江哈尔滨150006 [2]中国中医科学院中药资源中心道地药材品质保障与资源持续利用全国重点实验室,北京100700

出　　处：《中国中药杂志》2024年第22期6048-6065,共18页China Journal of Chinese Materia Medica

基　　金：国家自然科学基金项目(82373987);中国中医科学院科技创新工程项目(CI2023E002)。

摘　　要：五加属植物包含多种药用植物,在医药卫生、经济、食品等领域具有重要的价值,该属植物资源分布广泛,具有丰富的次生代谢物。目前在该属植物中报道的次生代谢物包括萜类、酚酸类、黄酮类、木脂素类等多种类型,具有抗炎、抗肿瘤、抗氧化、神经保护等药理活性,其中五加属三萜类成分备受关注。该文对五加属植物的资源分布与物种分类、次生代谢物以及药理活性的研究进展进行了综述,并对其生态学意义、药理活性开发及未来研究方向进行讨论与展望,以期为该属植物在物种保护、药物研发和疾病治疗等方面提供参考。The genus Eleutherococcus includes multiple medicinal plants that hold significant value in the fields of medicine,health,economy,and food.The resources of this genus are widely distributed and rich in secondary metabolites.The secondary metabolites reported in Eleutherococcus plants include various types,such as terpenoids,phenolic acids,flavonoids,and lignans,which exhibit pharmacological activities such as anti-inflammatory,anti-tumor,antioxidant,and neuroprotective effects.Among these,the triterpenoid components in Eleutherococcus plants have garnered significant attention.This review summarized the research progress on the resource distribution,species classification,secondary metabolites,and pharmacological activities of Eleutherococcus plants and discussed their ecological significance,pharmacological development,and future research directions,with the aim of providing references for species conservation,drug development,and disease treatment involving Eleutherococcus plants.

关 键 词：五加属 资源分布 次生代谢物 药理活性 

分 类 号：R282.71[医药卫生—中药学]