2013-2023年广安市HIV感染者及AIDS患者死亡病例分析  

Analysis of death cases of HIV infections and AIDS patients in Guang an from 2013 to 2023

作　　者：田彩虹 秦小佳 张军[1] 龚毅[2] 赵智蓉 TIAN Caihong;QIN Xiaojia;ZHANG Jun;GONG Yi;ZHAO Zhirong(Guang an Disease Prevention and Control Center,Guang an 638000,China;Sichuan Provincial Disease Prevention and Control Center,Chengdu 610000,China;Kunming Third People's Hospital,Kunming 650200,China)

机构地区：[1]广安市疾病预防控制中心,四川广安638000 [2]四川省疾病预防控制中心,四川成都610000 [3]昆明市第三人民医院,云南昆明650200

出　　处：《中国麻风皮肤病杂志》2025年第1期23-28,共6页China Journal of Leprosy and Skin Diseases

基　　金：昆明市卫生科技人才培养项目[编号:2021-SW(后备)-0030]。

摘　　要：收集2013-2023年国家艾滋病综合防治信息系统报告的广安市HIV/AIDS病例资料,运用Logistic回归模型分析HIV/AIDS病例死亡的影响因素。结果示广安市2013-2023年累计报告HIV/AIDS病例8803例,死亡2489例,病死率为28.27%。死亡病例中,AIDS占61.91%,男性占86.86%,确诊年龄在55岁及以上占68.62%,农民占72.32%,有配偶占55.56%,小学以下文化程度占74.25%,异性性传播占95.22%,医疗机构来源占73.04%,首次CD4^(+)T淋巴细胞未查者和小于200个/μL占62.43%,未行抗病毒治疗(antiretroviral therapy,ART)和ART不及时者占66.05%。多因素Logistic回归分析结果显示,HIV、女性、有配偶、来源于非医疗机构、确诊年龄<35岁、治疗及时的病例死亡概率较低;文化程度为小学及以下、确诊年龄≥55岁、首次就诊未检查CD4^(+)T淋巴细胞、未治疗的病例死亡概率较高。不论是HIV感染者还是AIDS患者,治疗组存活时长显著高于未治疗组(P<0.05)。The data came from the case information of HIV/AIDS cases in Guang an City reported by the National AIDS Comprehensive Prevention and Control Information System(NACIS)from 2013 to 2023.The influencing factors of deaths of HIV/AIDS cases were analysed by using logistic regression model.The results showed there were 8803 cases of HIV/AIDS in Guang'an City from 2013 to 2023,with 2489 deaths,the case-fatality rate was 28.27%.Of the deaths,AIDS accounted for 61.91%,males for 86.86%,diagnoses at age 55 and above for 68.62%,farmers for 72.32%,individuals with spouses for 55.56%,education levels below primary school for 74.25%,heterosexual transmission for 95.22%,medical institutions for 73.04%,first CD4^(+)T lymphocyte counts not examined or less than 200 cells/μL for 62.43%,and those not receiving antiretroviral therapy(ART)or with delayed ART for 66.05%.Results from the multivariate Logistic regression analysis showed that HIV infection,being female,spouse,being from non-medical institutions,age at diagnosis<35 years old and timely treatment were associated with lower probability of death.Cases with education level of primary school or below,age at diagnosis≥55,without CD4^(+)T lymphocyte examination at the first visit,and untreated had a higher probability of death.Both HIV-infected individuals and AIDS patients in the treatment group had significantly longer survival times than those in the untreated group(P<0.05).

关 键 词：获得性免疫缺陷综合征 死亡病例特征 抗病毒治疗 

分 类 号：R512.91[医药卫生—内科学]