大黄不同炮制品化学成分及药效差异的研究进展  

Research progress on chemical constituents and pharmacodynamic differences of different Rhubarb products

作　　者：王哲 王毛毛 马定财 王彦钧 张转红 刘婷[1] 高飞云 李越峰[1,2] WANG Zhe;WANG Maomao;MA Dingcai;WANG Yanjun;ZHANG Zhuanhong;LIU Ting;GAO Feiyun;LI Yuefeng(Gansu University of Chinese Medicine,Lanzhou,Gansu,730000 P.R.China;Scientific Research and Experimental Center,Gansu University of Chinese Medicine,Lanzhou,Gansu,730000 P.R.China)

机构地区：[1]甘肃中医药大学,甘肃兰州730000 [2]甘肃中医药大学科研实验中心,甘肃兰州730000

出　　处：《华西药学杂志》2024年第6期733-736,共4页West China Journal of Pharmaceutical Sciences

基　　金：国家自然科学基金资助项目(批准号:81960713,82160750);甘肃省教育厅产业支撑计划项目(2021CYZC-21);甘肃省科技计划(创新基地与人才计划)基础研究创新群体项目(21JR7RA569);2024年甘肃省人才重点项目(中药炮制技术传承创新团队建设与示范推广);高校产业支撑项目(2024CYZC-41);2024年甘肃省联合科研基金(红黄芪炮制增效机理及物质基础研究)。

摘　　要：大黄各炮制品间的各类化学成分含量存在不同程度的差异,其药效也会发生相应变化。现查阅相关文献,以鞣质、游离蒽醌、结合蒽醌和黄酮类成分为研究对象,对大黄不同炮制品间的化学成分和药效差异进行综述。There are differences in the contents of various chemical components among processed products of Rhubarb to some extent.The efficacy of the drug can also alter significantly.The relevant literature on the comparison between various processed products of rhubarb at home and abroad was sorted and analyzed.Tannins,free anthraquinones,combined anthraquinones and flavonoids were taken as the research objects,and the differences in chemical composition and efficacy between different processed products of rhubarb were reviewed.

关 键 词：大黄 炮制品 指标成分 药效 比较研究 质量标准 综述 

分 类 号：R917[医药卫生—药物分析学]