经颅重复针刺法联合翁沥通胶囊治疗良性前列腺增生疗效观察  

Effect of repetitive transcranial acupuncture stimulation acupuncture combined with Wenglitong capsule on benign prostatic hyperplasia

作　　者：赵会谢 刘永存[2] 刘国伟[3] 任晓捷 ZHAO Huixie;LIU Yongcun;LIU Guowei;REN Xiaojie(Department of Vascular Surgery,Shijiazhuang Hospital of Traditional Chinese Medicine,Shijiazhuang,Hebei 050000;Department of Surgery,Shijiazhuang Hospital of Traditional Chinese Medicine,Shijiazhuang,Hebei 050000;Department of Acupuncture and Massage,Shijiazhuang Hospital of Traditional Chinese Medicine,Shijiazhuang,Hebei 050000;Department of Pulmonary Function,Hebei Chest Hospital,Shijiazhuang,Hebei 050000)

机构地区：[1]河北省石家庄市中医院脉管科,河北石家庄050000 [2]河北省石家庄市中医院外科,河北石家庄050000 [3]河北省石家庄市中医院针灸推拿科,河北石家庄050000 [4]河北省胸科医院肺功能科,河北石家庄050000

出　　处：《河北中医》2024年第12期2001-2004,2009,共5页Hebei Journal of Traditional Chinese Medicine

基　　金：河北省中医药管理局科研计划项目(编号:2020345);河北省中医药管理局科研计划项目(编号:2023372);石家庄市科学技术研究与发展计划项目(编号:221200373)。

摘　　要：目的观察经颅重复针刺法联合翁沥通胶囊治疗良性前列腺增生的疗效。方法将60例肾虚血瘀型良性前列腺增生患者按照随机数字表法分为对照1组、对照2组、治疗组,每组20例。对照1组予翁沥通胶囊,连续服用2个月;对照2组予经颅重复针刺法治疗,隔日1次,治疗2个月;治疗组予经颅重复针刺法联合翁沥通胶囊治疗,治疗2个月。比较2组临床疗效,以及治疗前后国际前列腺症状评分(IPSS)、前列腺体积、前列腺特异抗原(PSA)水平、睾酮水平及中医证候积分变化。结果对照1组总有效率75%(15/20),对照2组总有效率80%(16/20),治疗组总有效率90%(18/20),治疗组总有效率高于对照1组和对照2组(P<0.05),对照1组与对照2组比较差异无统计学意义(P>0.05)。治疗后,3组中医证候积分及IPSS评分均较本组治疗前降低(P<0.05),且治疗组低于对照1组和对照2组(P<0.05);治疗后,对照1组中医证候积分及IPSS评分与对照2组比较差异无统计学意义(P>0.05)。治疗后,3组前列腺体积较本组治疗前无明显变化(P>0.05),且治疗后3组组间比较差异也无统计学意义(P>0.05);3组差值比较差异也无统计学意义(P>0.05)。治疗后,3组睾酮水平均较本组治疗前无明显变化(P>0.05),且治疗后3组组间比较差异也均无统计学意义(P>0.05)。治疗后,治疗组PSA水平较本组治疗前降低(P<0.05),对照1组和对照2组PSA水平较本组治疗前无明显变化(P>0.05);治疗后3组组间PSA水平比较差异均无统计学意义(P>0.05)。结论经颅重复针刺法联合翁沥通胶囊治疗良性前列腺增生能明显改善患者症状,提高疗效,效果优于翁沥通胶囊和经颅重复针刺法单独治疗。Objective To observe the curative effect of repetitive transcranial acupuncture stimulation(rTAS)acupuncture combined with Wenglitong capsule on benign prostatic hyperplasia(BPH).Methods Sixty patients with BPH with kidney deficiency and blood stasis were randomized 1∶1∶1 to receive Wenglitong capsule(control group 1),rTAS acupuncture on alternate days(control group 2),or rTAS acupuncture+Wenglitong capsule(treatment group)by a random number table for 2 months.The clinical effects,international prostate symptom score(IPSS),prostate volume,prostate specific antigen(PSA)level,testosterone level and traditional Chinese medicine(TCM)syndrome score were assessed before and after treatment.Results The overall effective rate was significantly higher in the treatment group(90%[18/20])than in the control group 1(75%[15/20])and control group 2(80%[16/20])(P<0.05),which was found no significant difference from the control group 1 vs the control group 2(P>0.05).After treatment,TCM syndrome score and IPSS score in the three groups were significantly decreased than those before treatment(P<0.05),the decrease in the treatment group was more common than the control group 1 and control group 2(P<0.05).None of the TCM syndrome score and IPSS score differed significantly between control group 1 and control group 2(P>0.05).The difference was not statistically significant in the prostate volume in the three groups before and after treatment(P>0.05),and with no significant differences in pairwise comparisons(P>0.05).There was no statistically significant difference in the differential values among the three groups(P>0.05).The difference was not statistically significant in the testosterone level in the three groups before and after treatment(P>0.05),and with no significant differences in pairwise comparisons(P>0.05).After treatment,the PSA level was significantly decreased in the treatment group compared with before treatment(P<0.05),which was found no significant difference from the control group 1 vs the control group 2(P>0.05).

关 键 词：前列腺增生 肾虚血瘀 经颅刺激 穴位 头针刺激区 中成药 

分 类 号：R697.320.5[医药卫生—泌尿科学]