动态增强MRI乳腺背景实质强化的临床应用进展  

Clinical Application Progress of Dynamic Contrast-Enhanced MRI in Breast Background Parenchymal Enhancement

作　　者：李思叶 黄子康 沈君 徐滨 于越洋 朱玉春 LI Siye;HUANG Zikang;SHEN Jun;XU Bin;YU Yueyang;ZHU Yuchun(Gusu School,Nanjing Medical University,Suzhou Jiangsu 215002,China;Department of Radiology,The First People’s Hospital of Kunshan,Suzhou Jiangsu 215300,China;Department of Nuclear Medicine,The First People’s Hospital of Kunshan,Suzhou Jiangsu 215300,China;School of Medicine,Jiangsu University,Zhenjiang Jiangsu 212013,China;Department of Ultrasound,The Second People’s Hospital of Kunshan,Suzhou Jiangsu 215300,China)

机构地区：[1]南京医科大学姑苏学院,江苏苏州215002 [2]昆山市第一人民医院放射科,江苏苏州215300 [3]昆山市第一人民医院核医学科,江苏苏州215300 [4]江苏大学医学院,江苏镇江212013 [5]昆山市第二人民医院超声科,江苏苏州215300

出　　处：《中国医疗设备》2024年第12期159-164,177,共7页China Medical Devices

基　　金：2022年度省部共建放射医学与辐射防护国家重点实验室开放课题(苏州大学)(GZK1202219);江苏大学2023年度医教协同创新基金一般项目(JDYY2023060)。

摘　　要：乳腺癌在女性恶性肿瘤中发病率较高,且呈逐年上升的趋势。乳腺动态增强MRI中的背景实质强化(Background Parenchymal Enhancement,BPE)可作为促进乳腺病变定向精准诊断和治疗可持续发展的影像生物学标志物。BPE指乳腺正常纤维腺体的强化受多种因素影响,包括乳腺血供情况和机体内外源激素等。本文综述了BPE的分类及定量测量、BPE的影响因素、BPE与乳腺癌发病风险的相关性、BPE与乳腺癌新辅助化疗及预后的关系。Breast cancer has a high incidence rate among female malignant tumors,and the this rate is showing an increasing trend year by year.Background parenchymal enhancement(BPE)in breast dynamic contrast-enhanced MRI can be used as an image biomarker for promoting the targeted,precise diagnosis and treatment of breast lesions for sustainable development.BPE refers to the enhancement of normal fibroglandular breast tissue,influenced by various factors including breast blood supply,endogenous and exogenous hormones.This paper reviewed the classification and quantitative measurement of BPE,factors influencing BPE,the correlation between BPE and the risk of breast cancer,as well as the relationship between BPE,neoadjuvant chemotherapy for breast cancer,and prognosis.

关 键 词：背景实质强化 乳腺癌 乳腺动态增强磁共振 乳腺癌分子亚型 新辅助化疗 

分 类 号：R445.2[医药卫生—影像医学与核医学] R197.3[医药卫生—诊断学]