Global hotspots and future directions for drugs to improve the skin flap survival: A bibliometric and visualized review  

作　　者：Shuangmeng Jia Jieshen Huang Wuyan Lu Yongen Miao Kehua Huang Chenzhang Shi Shuaijun Li Jiefeng Huang 

机构地区：[1]Department of Plastic Surgery,Shanghai Tenth People's Hospital,Tongji University School of Medicine,Shanghai,200092,China [2]School&Hospital of Stomatology,Shanghai Engineering Research Center of Tooth Restoration and Regeneration,Tongji University,Shanghai,200072,China [3]Mudanjiang Medical University,Mudanjiang,Heilongjiang,157011,China [4]Shenzhen Children's Hospital,Shenzhen,Guangdong,518026,China [5]Department of Gastrointestinal Surgery,Shanghai Tenth People's Hospital,Tongji University,Shanghai,200072,China

出　　处：《Journal of Pharmaceutical Analysis》2024年第7期972-982,共11页药物分析学报（英文版）

基　　金：funded by the National Natural Science Foundation of China(Grant No.:82070533).

摘　　要：Skin flaps are frequently employed in plastic and reconstructive surgery to address tissue defects.However,their low survival rates remain a challenge,attributed to vascular crisis and necrosis.Despite numerous studies investigating drugs to alleviate flap necrosis,a comprehensive analysis of the research trend in this critical area is lacking.To gain a deeper understanding of the current status,research focal points,and future trends in drugs aimed at enhancing flap survival,a thorough retrospective analysis is imperative.This study aims to employ bibliometric methods to scrutinize the evolution,mechanisms,and forthcoming trends of drugs targeting flap survival improvement.Using VOSviewer software,we quantitatively and visually depict 1)annual temporal trends in the number of documents and citations;2)national/regional publications and their collaborations;3)institutional and authors’contribution;4)journal contribution and relevance;and 5)analysis of research hotspots and directions derived from keywords.Ultimately,we discussed the prospects and challenges of future advances and clinical translation of drugs designed to enhance skin flap survival.In conclusion,the field of pharmacology dedicated to improving skin flap survival is expanding,and this study aims to offer a fresh perspective to promote the advancement and clinical application of such drugs.

关 键 词：Skin flap Drug therapy Bibliometric analysis Global trends 

分 类 号：R917[医药卫生—药物分析学]