从纤维化探讨血竭、三七“以通求固”治疗子宫腺肌病的机制  

Exploring Mechanism of Treating Adenomyosis with Xuejie(Draconis Sanguis)and Sanqi(Notoginseng Radix et Rhizoma)through Fibrosis

作　　者：陆黎娟[1] 曾薇薇[2] 孙博 孙薛亮[1] 张露蓉[1] 张婷婷[4] LU Lijuan;ZENG Weiwei;SUN Bo;SUN Xueliang;ZHANG Lurong;ZHANG Tingting(Suzhou Hospital of Traditional Chinese Medicine Affiliated to Nanjing University of Chinese Medicine,Suzhou 215000,Jiangsu,China;Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 200120,China;Fangta Traditional Chinese Medicine Hospital of Songjiang District,Shanghai 201600,China;Yueyang Hospital of Integrated Chinese and Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 200080,China)

机构地区：[1]南京中医药大学附属苏州市中医医院,江苏苏州215000 [2]上海中医药大学附属曙光医院,上海200120 [3]上海市松江区方塔中医医院,上海201600 [4]上海中医药大学附属岳阳中西医结合医院,上海200080

出　　处：《辽宁中医杂志》2024年第12期32-35,共4页Liaoning Journal of Traditional Chinese Medicine

基　　金：国家自然科学基金项目(82004398);苏州市科技发展计划(医疗卫生科技创新)项目(SKY2022205,SKYXD2022058);苏州市科技计划(医学创新应用研究)项目(SKY2023213);苏州市卫生青年骨干人才“全国导师制”培训项目(苏卫健科教[2020]7号);上海市松江区科学技术攻关项目(21SJKJGG120)。

摘　　要：子宫腺肌病为育龄期女性常见病、多发病之一,月经量多、痛经为其主要临床表现,进行性增大的子宫和月经过多最终导致重度贫血,严重影响女性身心健康。临床运用发现蔡氏妇科“以通求固”思想治疗子宫腺肌病,代表药物为血竭、三七,明显改善患者月经量多、痛经症状。现将现代医学研究与中医理论相结合,尝试从纤维化角度探索“以通求固”思想治疗子宫腺肌病作用机制,为中医药治疗子宫腺肌病提供新思路。Adenomyosis is one of the common and frequently-occurring diseases in women of childbearing age,with menorrhagia and dysmenorrhea as its main clinical manifestations.Progressive enlargement of uterus and menorrhagia eventually leads to severe anemia,which seriously affects women′s physical and mental health.Clinical application has found that Cai′s gynaecology uses the concept of“seeking consolidation by dredging”was used to treat adenomyosis,and the representative drugs were Xuejie(Draconis Sanguis)and Sanqi(Notoginseng Radix et Rhizoma),which obviously improved the symptoms of menorrhagia and dysmenorrhea.Combining modern medical research with traditional Chinese medicine theory,this paper tried to explore the mechanism of treating adenomyosis from the perspective of fibrosis,and provided new ideas for treating adenomyosis with traditional Chinese medicine.

关 键 词：子宫腺肌病 以通求固 纤维化 血竭 三七 理论探讨 

分 类 号：R271[医药卫生—中医妇科学]