天麻葛根汤联合倍他司汀治疗后循环缺血性眩晕风痰瘀阻证临床观察  

Clinical Observation on Tianma Gegen Decoction(天麻葛根汤)Combined with Betaestine in Treatment of Wind-Phlegm and Blood Stasis Syndrome of Posterior Circulation Ischemic Vertigo

作　　者：黄黎娟 邓奕辉[1] HUANG Lijuan;DENG Yihui(Hunan University of Traditional Chinese Medicine,Changsha 410208,Hunan,China)

机构地区：[1]湖南中医药大学,湖南长沙410208

出　　处：《辽宁中医杂志》2024年第12期53-56,共4页Liaoning Journal of Traditional Chinese Medicine

基　　金：国家自然科学基金面上项目(81874416);湖南省科技创新团队项目(2020RC4050)。

摘　　要：目的对天麻葛根汤联用倍他司汀治疗后循环缺血性眩晕风痰瘀阻证的临床效果进行观察和分析。方法将长沙康德医院60例后循环缺血性眩晕风痰瘀阻证患者,按随机数字表法分为治疗组和对照组,每组30例。治疗组采用天麻葛根汤与倍他司汀联合治疗,对照组则单用倍他司汀治疗,记录两组患者的临床疗效、中医证候积分、眩晕障碍评估量表(dizziness handicap inventory,DHI)评分、眩晕评定量表的评分系统(dizziness assessment rating scale,DARS)评分变化及治疗前后的不良反应发生率。结果治疗组中医证候疗效总有效率100%(30/30),与对照组93.34%(28/30)比较,差异有显著统计学意义(P<0.01);两组患者治疗后眩晕、头痛、耳鸣、恶心、颈项僵硬、肢体麻木乏力、行走不稳等症状的证候积分明显下降,治疗组中医证候积分下降更为明显,二者之间的差异具有统计学意义(P<0.05);观察治疗后DHI评分和DARS评分降低幅度均优于对照组(P<0.05)。治疗组不良反应发生率为6.67%(2/30),与对照组20%(5/30)比较有所下降,但差异无统计学意义(P<0.05)。结论天麻葛根汤联合倍他司汀治疗后循环缺血性眩晕风痰瘀阻证较单用倍他司汀疗效更好。Objective To observe and analyze the clinical effect of Tianma Gegen Decoction(天麻葛根汤)combined with betaestine in the treatment of wind-phlegm and blood stasis syndrome of posterior circulation ischemic vertigo.Methods Sixty patients with wind-phlegm and blood stasis syndrome of posterior circulation ischemic vertigo were divided into treatment group and control group with 30 patients in each group.In the treatment group,the combination of Tianma Gegen Decoction and betaetine was used,while the control group was treated with betaetine alone.The clinical efficacy of both groups,TCM syndrome scores,the score of dizziness handicap inventory(DHI),dizziness assessment rating scale(DARS)and the incidence of adverse reactions before and after treatment were recorded.Results The total effective rate of TCM syndrome in the treatment group was 100%(30/30),compared with that[93.34%(28/30)]in the control group(P<0.01).The scores of dizziness,headache,tinnitus,nausea,neck stiffness,numbness and walking of two groups after treatment were obviously decreased,and the decrease in the treatment group was more obvious and the difference was statistically significant(P<0.05).The decrease in DHI score and DARS score in the treatment group was better than that of the control group(P<0.05).The incidence of adverse effects was 6.67%(2/30)in the treatment group.Compared with that[20%(5/30)]in the control group,there was no statistical significance(P<0.05).Conclusion Tianma Gegen Decoction combined with betaestine had a better effect than betazetine alone.

关 键 词：天麻葛根汤 倍他司汀 后循环缺血性眩晕 风痰瘀阻证 

分 类 号：R255.3[医药卫生—中医内科学]