青霉素钠联合头孢噻肟钠治疗新生儿肺炎的临床效果分析  

Analysis of Clinical Effect of Benzylpenicillin Sodium and Cefotaxime Sodium in Treatment of Neonatal Pneumonia

作　　者：宁丽萍 Ning Liping(People's Hospital of Shaodong,Shaodong 422213,Hunan Province,China)

机构地区：[1]邵东市人民医院,湖南邵东422213

出　　处：《中国社区医师》2024年第33期20-22,共3页Chinese Community Doctors

摘　　要：目的:分析青霉素钠联合头孢噻肟钠治疗新生儿肺炎的临床效果。方法:将2019年5月—2021年5月邵东市人民医院收治的80例新生儿肺炎患儿作为研究对象,按照随机数字表法分为两组,每组40例。两组患儿均进行常规基础治疗,对照组采用头孢噻肟钠治疗,研究组在对照组基础上采用青霉素钠治疗,比较两组临床疗效、炎性因子水平、临床指标、不良反应发生情况。结果:和对照组相比,研究组治疗总有效率更高(P<0.05)。治疗前,两组C反应蛋白、降钙素原、白细胞水平对比,差异无统计学意义(P>0.05);治疗后,两组C反应蛋白、降钙素原、白细胞水平降低,且研究组低于对照组(P<0.05)。研究组症状缓解时间、机械辅助通气时间比对照组短(P<0.05)。和对照组相比,研究组不良反应总发生率更低(P<0.05)。结论:青霉素钠联合头孢噻肟钠治疗新生儿肺炎的临床效果良好,可减轻患儿炎性反应,缓解临床症状,减少不良反应。Objective:To analyze the clinical effect of benzylpenicillin sodium and cefotaxime sodium in treatment of neonatal pneumonia.Methods:A total of 80 children with neonatal pneumonia admitted to the People's Hospital of Shaodong between May 2019 and May 2021 were included as study subjects.They were divided into two groups according to random number table method,with 40 cases in each group.The children in both groups received conventional basic treatment,the control group was treated with cefotaxime sodium,and the study group was treated with benzylpenicillin sodium on the basis of the control group.The clinical efficacy,levels of inflammatory factors,clinical indicators,and occurrence of adverse reactions were compared between the two groups.Results:The total effective rate of treatment in the study group was higher than that in the control group(P<0.05).Before treatment,there was no statistically significant difference in the levels of C-reactive protein,procalcitonin and leukocyte between the two groups(P>0.05).After treatment,the levels of C-reactive protein,procalcitonin and leukocyte in the two groups decreased,and the levels in the study group were lower than those in the control group(P<0.05).The time of symptom relief and the time of assisted mechanical ventilation in the study group were shorter than those in the control group(P<0.05).The total incidence of adverse reactions in the study group was lower than that in the control group(P<0.05).Conclusion:Benzylpenicillin sodium and cefotaxime sodium has good clinical effect in the treatment of neonatal pneumonia,and can relieve inflammatory reactions,alleviate clinical symptoms and reduce adverse reactions in children.

关 键 词：新生儿肺炎 头孢噻肟钠 青霉素钠 

分 类 号：R722.135[医药卫生—儿科]