等离子电切镜在前列腺增生患者手术治疗中的临床研究  

The Effect of Plasma Electrocautery on Sexual Function and Inflammatory Cytokine Levels in Patients with Benign Prostatic Hyperplasia

作　　者：吴钦福 李昌宇 Wu Qinfu;Li Changyu(Fujian Medical University Affiliated Longyan First Hospital,Fujian Longyan 364000,China)

机构地区：[1]福建医科大学附属龙岩第一医院,福建龙岩364000

出　　处：《医疗装备》2024年第20期1-4,9,共5页Medical Equipment

摘　　要：目的探讨等离子电切镜在前列腺增生患者手术治疗中的应用效果。方法选择2022年3月至2024年1月医院就诊的110例行前列腺增生手术的患者,采用随机数字表法分为对照组和试验组,每组55例。对照组使用普通电切镜进行手术,试验组使用等离子电切镜进行手术,比较两组围手术期指标(术中出血量、手术时间、尿管留置时间、住院时间)、性功能障碍(性欲下降、阴茎硬度降低、勃起障碍、射精障碍)发生率、炎症因子[肿瘤坏死因子-α(TNF-α)、白细胞介素-1β(IL-1β)、IL-2、IL-6]水平及并发症发生率。结果试验组术中出血量少于对照组,手术时间、尿管留置时间短于对照组,差异有统计学意义(P<0.05);试验组性功能障碍发生率低于对照组,差异有统计学意义(P<0.05);术后1 d,试验组TNF-α、IL-1β、IL-2、IL-6水平低于对照组,差异有统计学意义(P<0.05);试验组并发症发生率低于对照组,差异有统计学意义(P<0.05)。结论等离子电切镜用于前列腺增生手术患者中,可以减轻对机体的损伤,促进术后恢复,降低性功能障碍及并发症发生率,抑制炎症因子水平。Objective To investigate the effects of plasma assisted resection of the prostate in patients with benign prostatic hyperplasia.Methods A total of 110 patients with benign prostatic hyperplasia who visited the hospital from March 2022 to January 2024 were selected and randomly divided into a control group and an experimental group used a random number table method,with 55 patients in each group.The control group used a regular electrocautery,while the experimental group used a plasma electrocautery.The perioperative indicators(intraoperative blood loss,surgery time,catheterization time,hospital stay),incidence of sexual dysfunction(decreased libido,decreased penile hardness,erectile dysfunction,ejaculation dysfunction),levels of inflammatory factors(tumor necrosis factor-α)(TNF-α),interleukin-1β(IL-1β),IL-2,IL-6,and incidence of complications were compared between the two groups.Results The experimental group had less intraoperative bleeding than the control group,and the operation time and indwelling time of the urinary catheter were shorter than those of the control group,with statistically significant differences(P<0.05);The incidence of sexual dysfunction in the experimental group was lower than that in the control group,and the difference was statistically significant(P<0.05);On postoperative day 1,the levels of TNF-α,IL-1β,IL-2,and IL-6 in the experimental group were lower than those in the control group,and the differences were statistically significant(P<0.05);The incidence of complications in the experimental group was lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion Plasma electrosurgical treatment for benign prostatic hyperplasia can reduce body damage,promote postoperative recovery,lower the incidence of sexual dysfunction and complications,and inhibit levels of inflammatory factors.

关 键 词：等离子电切镜 前列腺增生 性功能 炎症因子 性功能障碍 并发症 

分 类 号：R699.8[医药卫生—泌尿科学]