药学干预对抗生素使用情况的影响  

The Impact of Pharmaceutical Intervention on the Use of Antibiotics

作　　者：庄玉凤 吕纬苓 官毅红 ZHUANG Yufeng;LU Weiling;GUAN Yihong(Department of Pharmacy,Shuangyang Community Health Service Center of Luojiang District,Quanzhou,362000,China;College of Integrated Traditional Chinese and Western Medicine,Fujian University of Traditional Chinese Medicine,Fuzhou,350108,China;Department of Pharmacy,Xinglin Branch of The First Affiliated Hospital of Xiamen University,Xiamen,361000,China)

机构地区：[1]泉州市洛江区双阳社区卫生服务中心药剂科,泉州362000 [2]福建中医药大学中西医结合学院,福州350108 [3]厦门大学附属第一医院杏林院区药剂科,厦门361000

出　　处：《中国医药指南》2024年第35期46-48,共3页Guide of China Medicine

摘　　要：目的研究抗生素类药物在使用过程中对患者实施药学干预的临床价值。方法选取2021年1月至2023年12月在泉州市洛江区双阳社区卫生服务中心就诊并采用抗生素类药物实施治疗的患者120例,采用随机数字表法将其分成两组。对照组(60例)接受常规用药干预,观察组(60例)接受药学干预,对比两组各项临床指标。结果观察组治疗依从率为96.67%,高于对照组的85.00%(P<0.05)。观察组药物不良反应总发生率为5.00%,低于对照组的40.00%(P<0.05)。观察组不合理用药总发生率为3.33%,低于对照组的40.00%(P<0.05)。观察组总体满意度为100.00%,高于对照组的80.00%(P<0.05)。观察组持续用药时间、用药费用及用药种类均少于对照组(P<0.05)。干预后,观察组药学服务质量评分和相关知识了解程度评分均高于对照组(P<0.05)。结论在抗生素类药物在使用过程中,对患者实施药学干预,能够减少用药期间不良反应,防止不合理用药情况发生,改善药学服务质量。Objective This study aimed to investigate the clinical efficacy of pharmaceutical interventions during antibiotic use in patients.Methods A total of 120 patients who visited Shuangyang Community Health Service Center in Luojiang District,Quanzhou,and were treated with antibiotics from January 2021 to December 2023 were selected and divided into two groups using the random number table method.The control group(60 cases)received conventional medication intervention,and the observation group(60 cases)received pharmaceutical intervention,with a comparison of various clinical indicators between the two groups.Results The medication adherence rate in the intervention group reached 96.67%,significantly higher than the control group's 85.00%(P<0.05).The incidence of adverse drug reactions in the intervention group was 5.00%,significantly lower than the control group's 40.00%(P<0.05).The rate of irrational drug use in the intervention group was 3.33%,also significantly lower than the control group's 40.00%(P<0.05).Patient satisfaction in the intervention group was 100.00%,significantly higher than the control group's 80.00%(P<0.05).Furthermore,the intervention group had shorter durations of medication use,lower costs,and fewer types of medications compared to the control group(P<0.05).After intervention,the intervention group scored higher than the control group in both pharmaceutical service quality and level of knowledge acquisition(P<0.05).Conclusions Pharmaceutical interventions for patients on antibiotics can effectively reduce adverse drug reactions,prevent irrational medication use,and enhance the overall quality of pharmaceutical services.

关 键 词：药学干预 抗生素 不合理用药 依从性 不良反应 

分 类 号：R969.3[医药卫生—药理学]