不同等级步行运动训练联合呼吸操训练在慢性阻塞性肺疾病患者中的应用效果  

Application Effect of Different Levels of Walking Exercise Training Combined with Breathing Exercise Training in Patients with Chronic Obstructive Pulmonary Disease

作　　者：杨冬玉 石磊 周清和 赵云青 YANG Dongyu;SHI Lei;ZHOU Qinghe;ZHAO Yunqing(Department of Respiratory and Critical Care Medicine,Yellow River Sanmenxia Hospital,Sanmenxia 472000,China;Department of Cardiology,Sanmenxia Traditional Chinese Medicine Hospital,Sanmenxia 472000,China;Department of Respiratory Therapy,Sir Run Run Shaw Hospital,Affiliated with the Zhejiang University School of Medicine,Hangzhou 310000,China)

机构地区：[1]黄河三门峡医院呼吸与危重症医学科,河南省三门峡市472000 [2]河南省三门峡市中医院心病科,472000 [3]浙江大学医学院附属邵逸夫医院呼吸治疗科,浙江省杭州市310000

出　　处：《实用心脑肺血管病杂志》2025年第1期108-113,共6页Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease

摘　　要：目的分析不同等级步行运动训练联合呼吸操训练在慢性阻塞性肺疾病(COPD)患者中的应用效果。方法选择2022年5月—2024年5月黄河三门峡医院呼吸与危重症医学科收治的COPD患者110例为研究对象。按照随机数字表法将患者分为对照组与观察组,每组55例。两组患者均接受雾化吸入治疗,此外,对照组接受不同等级步行运动训练,观察组接受不同等级步行运动训练联合呼吸操训练,共干预2周。比较两组干预前后运动耐力[采用6分钟步行距离(6MWD)评估]、胆碱酯酶(CHE)水平、白介素17(IL-17)水平、肺功能指标[第1秒用力呼气容积(FEV_(1))、用力肺活量(FVC)、FEV_(1)/FVC]、生活质量[采用圣乔治呼吸问卷(SGRQ)评估]。结果干预后,观察组6MWD长于对照组(P<0.05);对照组、观察组干预后6MWD分别长于本组干预前(P<0.05)。干预后,观察组CHE水平高于对照组,IL-17水平低于对照组(P<0.05);对照组、观察组干预后CHE水平分别高于本组干预前,IL-17水平分别低于本组干预前(P<0.05)。干预后,观察组FEV_(1)、FVC大于对照组,FEV_(1)/FVC高于对照组(P<0.05);对照组、观察组干预后FEV_(1)、FVC分别大于本组干预前,FEV_(1)/FVC分别高于本组干预前(P<0.05)。干预后,观察组SGRQ评分低于对照组(P<0.05);对照组、观察组干预后SGRQ评分分别低于本组干预前(P<0.05)。结论不同等级步行运动训练联合呼吸操训练可有效提升COPD患者的运动耐力,升高CHE水平,减轻炎症反应,改善肺功能,提高生活质量。Objective To analyze the application effect of different levels of walking exercise training combined with breathing exercise training in patients with chronic obstructive pulmonary disease(COPD).Methods A total of 110 COPD patients admitted to the Department of Respiratory and Critical Care Medicine of Yellow River Sanmenxia Hospital from May 2022 to May 2024 were selected as the research subjects.According to the random number table method,patients were divided into control group and observation group,with 55 cases in each group.Both groups of patients received nebulization therapy.In addition,the control group received different levels of walking exercise training,while the observation group received different levels of walking exercise training combined with breathing exercise training for a total of 2 weeks of intervention.The exercise endurance[evaluated by 6-minute walking distance(6MWD)],cholinesterase(CHE)levels,interleukin-17(IL-17)levels,lung function indicators[forced expiratory volume in one second(FEV_(1)),forced vital capacity(FVC),FEV_(1)/FVC]and quality of life[evaluated by St.George's Respiratory Questionnaire(SGRQ)]before and after intervention were compared between the two groups.Results After intervention,6MWD in the observation group was longer than that in the control group(P<0.05).In the control group and observation group,the 6MWD after intervention was longer than that before intervention,respectively(P<0.05).After intervention,CHE level in observation group was higher than that in control group,IL-17 level was lower than that in control group(P<0.05).In the control group and observation group,the CHE level after intervention was higher than that before intervention,while IL-17 level was lower than that before intervention,respectively(P<0.05).After intervention,FEV_(1) and FVC in observation group were larger than those in control group,FEV_(1)/FVC was higher than that in control group(P<0.05).In the control group and observation group,FEV_(1) and FVC after intervention were larger than

关 键 词：肺疾病 慢性阻塞性 步行运动训练 呼吸操训练 

分 类 号：R563.9[医药卫生—呼吸系统]