中药溻渍法治疗小儿肺炎喘嗽的疗效及对其肺功能的保护作用  

Efficacy of the Method of External Application and Soaking Treatment with Traditional Chinese Medicine in Treatment of Pediatric Pneumonia with Dyspnea and Cough and Its Protective Effect on Pulmonary Function

作　　者：吴胜[1] 符顺丹 陆晓丹 WU Sheng;FU Shun-dan;LU Xiao-dan(Department of Pediatrics,Hainan Traditional Chinese Medicine Hospital,Haikou Hainan 570203)

机构地区：[1]海南省中医院儿科,海南海口570203

出　　处：《世界中西医结合杂志》2024年第11期2257-2261,2268,共6页World Journal of Integrated Traditional and Western Medicine

基　　金：海南省卫生健康行业科研项目(20A200090)。

摘　　要：目的探讨中药溻渍法治疗小儿肺炎喘嗽的疗效及对其肺功能的保护作用。方法选取2021年3月—2023年3月期间海南省中医院收治的小儿肺炎喘嗽患儿102例,按1∶1比例随机分为对照组和观察组,每组各51例。对照组给予常规治疗,观察组在对照组基础上加用中药溻渍疗法,疗程7 d。观察比较两组患儿中医证候评分变化及症状消退时间,检测外周血白细胞计数(White blood cell count,WBC)、血清C反应蛋白(C-reactive protein,CRP)、降钙素原(Procalcitonin,PCT),监测肺功能指标[第一秒用力呼气容积(First second forced expiratory volume,FEV1)、FEV1占最大呼气容积(Forced vital capacity,FVC)的百分比(Percentage of FEV1 to FVC,FEV1/FVC)、呼吸峰值流速(Peak respiratory flow rate,PEF)],并比较两组患儿的综合临床疗效及不良反应。结果治疗后观察组退热时间、咳嗽、咳痰、气喘及肺啰音消失的平均时间均明显缩短,差异有统计学意义(P<0.05)。治疗后两组患儿主要症状体征及中医证候积分均较治疗前降低,差异有统计学意义(P<0.05);且观察组主要症状体征及中医证候积分均明显低于对照组,差异有统计学意义(P<0.05)。治疗后两组患儿WBC、CRP和PCT水平均较治疗前降低,差异有统计学意义(P<0.05);且观察组WBC、CRP和PCT水平均明显低于对照组,差异有统计学意义(P<0.05)。治疗后两组患儿FEV1、FEV1/FVC和PEF值均较治疗前升高,差异有统计学意义(P<0.05);且观察组FEV1、FEV1/FVC和PEF值均明显高于对照组,差异有统计学意义(P<0.05)。治疗后观察组愈显率94.12%(48/51)明显高于对照组82.35%(42/51),差异有统计学意义(P<0.05)。治疗期间,两组患儿均未出现明显不良反应情况。结论中药溻渍法治疗小儿肺炎喘嗽可促进病情缓解,提高临床疗效。Objective To investigate the efficacy of the method of external application and soaking treatment with traditional Chinese medicine in treatment of pediatric pneumonia with dyspnea and cough and its protective effect on pulmonary function.Methods A total of 102 children suffering from pediatric pneumonia with dyspnea and cough who were treated in Hainan Traditional Chinese Medicine Hospital between March 2021 and March 2023 were selected and randomly divided into two groups:51 children in the control group were given routine treatment,while 51 children in the observation group were treated by the method of external application and soaking treatment with traditional Chinese medicine on this basis,with a course lasting for 7 days.The changes in traditional Chinese medicine syndrome scores and symptom resolution time were compared between the two groups of children.The peripheral white blood cell count(WBC),serum C-reactive protein(CRP),and procalcitonin(PCT)were detected.The pulmonary function indicators[first second forced expiratory volume(FEV1),ratio of FEV1 to forced vital capacity(FVC)(FEV1/FVC),and peak expiratory flow(PEF)]were monitored.The comprehensive clinical efficacy and adverse reactions of the two groups of children were compared.Results After treatment,the time for fever clearance of the observation group was significantly earlier than that of the control group,and the time for cough,expectoration,dyspnea,and lung rale disappearance of the observation group was significantly shortened,compared with that of the control group(P<0.05).The main symptom and sign scores of traditional Chinese medicine syndrome scores of the two groups were significantly reduced after treatment compared to before treatment(P<0.05).Compared with those of the control group,the main symptom and sign scores of traditional Chinese medicine syndrome scores of the observation group decreased significantly(P<0.05).After treatment,the WBC,CRP,and PCT of the two groups were significantly reduced compared to those before treatment(P<

关 键 词：小儿 肺炎 喘嗽 中药 溻渍法 肺功能 

分 类 号：R563.1[医药卫生—呼吸系统]