基于“浊邪害清”探讨流感病毒感染机制  

Exploring the Mechanism of Influenza Virus Infection Based on"Turbid Evils Invading the Clear Orifice"

作　　者：曲根生 刘光华[1] QU Gensheng;LIU Guanghua(Liaoning University of Traditional Chinese Medicine,Shenyang 110847,Liaoning,China)

机构地区：[1]辽宁中医药大学,辽宁沈阳110847

出　　处：《实用中医内科杂志》2024年第12期28-31,共4页Journal of Practical Traditional Chinese Internal Medicine

基　　金：国家自然科学基金青年科学基金项目(81403293)。

摘　　要：清浊相因,升降有序是维持人体先天免疫系统功能的基础,流感病毒(Ⅳ)感染通过多种调节机制迅速诱发宿主先天免疫反应,过度的炎性反应将导致宿主免疫致病。该文围绕流感病毒感染分三个部分展开论述。一是Ⅳ的发病机制,涉及患者机体清浊升降失衡、痰瘀互扰、免疫损伤;二是治疗方法,包括升清降浊调节的理论依据及甘露消毒丹、升降散等方剂作用机制;三是现代机制研究,体现中药多靶点调节防止Ⅳ。旨在为临床防治Ⅳ提供思路。The interdependence of the clear and turbid,and the orderly ascending and descending are the foundation for maintaining the function of the human innate immune system.Influenza virus(Ⅳ)infection rapidly induces the host's innate im⁃mune response through various regulatory mechanisms,and excessⅣe inflammatory responses will lead to host immune pathogen⁃esis.This article discusses the influenza virus infection in three parts.First,the pathogenesis ofⅣ,which involves the imbal⁃ance of the clear and turbid ascending and descending,the mutual disturbance of phlegm and stasis,and the immune damage in the patient's body.Second,the treatment methods,including the theoretical basis of regulating the ascending of the clear and de⁃scending of the turbid,and the mechanism of action of prescriptions such as Ganlu Xiaodu Dan and Shengjiang San.Third,mod⁃ern mechanism research,which reflects the multi-target regulation of traditional Chinese medicine to preventⅣ.The aim is to provide ideas for the clinical prevention and treatment ofⅣ.

关 键 词：流感病毒感染 浊邪害清 升清降浊 炎症 

分 类 号：R259[医药卫生—中西医结合]