射血分数保留型心力衰竭的诊疗进展  

Progress in diagnosis and treatment of heart failure with preserved ejection fraction

作　　者：潘怡婷 李岩松 丁胤彰 王凯 许迪 PAN Yiting;LI Yansong;DING Yinzhang;WANG Kai;XU Di(Department of Geriatric Cardiology,the First Affiliated Hospital of Nanjing Medical University,Nanjing,Jiangsu,210029)

机构地区：[1]南京医科大学第一附属医院老年心血管科,江苏南京210029

出　　处：《实用临床医药杂志》2024年第22期143-148,共6页Journal of Clinical Medicine in Practice

基　　金：国家自然科学基金资助项目(面上项目)(82071944)。

摘　　要：射血分数保留型心力衰竭(HFpEF)被定义为左心室射血分数(LVEF)≥50%,同时伴有钠尿肽(BNP)水平升高或其他充血证据。HFpEF有高发病率及高致死率的特点,现已超过射血分数减少型心力衰竭(HFrEF),成为心力衰竭的主流。本文对HFpEF的定义、流行病学、分类、诊断、病理、合并症及其治疗予以综述,旨在为临床研究提供证据。Heart failure with preserved ejection fraction(HFpEF)is defined as having a left ventricular ejection fraction(LVEF)of≥50%accompanied by elevated natriuretic peptide(BNP)levels or other evidence of congestion.HFpEF is characterized by high morbidity and mortality rates and has surpassed heart failure with reduced ejection fraction(HFrEF)to become the predominant form of heart failure.This article reviewed the definition,epidemiology,classification,diagnosis,pathology,comorbidities,and treatment of HFpEF,providing evidence for clinical research.

关 键 词：射血分数保留型心力衰竭 射血分数减少型心力衰竭 心力衰竭 炎症 内皮功能障碍 舒张功能障碍 

分 类 号：R541[医药卫生—心血管疾病] R459.1[医药卫生—内科学] R395[医药卫生—临床医学]