酮咯酸氨丁三醇与布托啡诺分别联合舒芬太尼在剖宫产术后镇痛中的应用效果  

The application effect of ketorolac tropanol and butorphanol ombined with sufentanil in postpartum analgesia of patients with cesarean section

作　　者：陈凤珍 袁从虎[1] 钱静[1] 唐月月 CHEN Feng-zhen;YUAN Cong-hu;QIAN Jing;TANG Yue-yue(Department of Anesthesiology,Yancheng Third People's Hospital,Yancheng 224001,Jiangsu,China)

机构地区：[1]盐城市第三人民医院麻醉科,江苏盐城224001

出　　处：《川北医学院学报》2024年第12期1676-1679,共4页Journal of North Sichuan Medical College

基　　金：江苏省中医药科技发展计划项目(YB2020080)。

摘　　要：目的:比较酮咯酸氨丁三醇(KT)与布托啡诺分别联合舒芬太尼在剖宫产术后镇痛中的应用效果。方法:选取102例剖宫产产妇为研究对象,依据术后使用镇痛药物不同分为A组(n=59)和B组(n=43)。A组产妇术后使用布托啡诺联合舒芬太尼镇痛;B组产妇术后使用KT联合舒芬太尼镇痛。比较两组产妇术后疼痛程度[视觉模拟评分法(VAS)评分]、镇静程度[Ramsay镇静评分量表(RSS)评分]、术后72 h内镇痛泵按压次数、术后恢复情况及不良反应发生情况。结果:B组产妇术后6、12、24 h VAS评分及术后4、8、12 h时镇痛泵按压次数及首次离床时间均低于A组(P<0.05);两组产妇术后各时间点RSS评分、胃肠道功能恢复时间、首次泌乳时间及不良反应总发生率比较,差异无统计学意义(P>0.05)。结论:KT与布托啡诺分别联合舒芬太尼对剖宫产产妇术后均具有良好镇痛、镇静作用,且不良反应发生风险均较低,但以KT联合舒芬太尼的镇痛效果更好。Objective:To explore the application effect of ketorolac tromethamine(KT)combined with sufentanil and butorphanol combined with sufentanil on postpartum analgesia in patients with cesarean section.Methods:The clinical data of 102 puerperae undergoing elective cesarean section were retrospectively analyzed.According to the analgesia administration after cesarean section,they were divided into group A(n=59,butorphanol)and group B(n=43,KT),each group combined with sufentanil.The pain degree[visual analogue scale(VAS)]and sedation degree[Ramsay sedation scale(RSS)]after operation were observed.The number of analgesic pump compressions within 72 h after operation were counted,the postoperative recovery and adverse reactions were recorded,and the safety was evaluated.Results:VAS scores at 6,12 and 24 h after surgery,the number of analgesic pump compressions at 4,8 and 12 h after surgery and first ambulation time in group B were lower or shorter than those in group A(P<0.05).There were no significant differences in RSS scores after surgery,gastrointestinal function recovery time,first lactation time and total incidence rate of adverse reactions during analgesia administration between groups(P>0.05).Conclusion:Both KT and butorphanol combined with sufentanil have good analgesic and sedative effects after cesarean section,and the risk of adverse reactions is low.The clinical analgesic effect of KT combined with sufentanil is more ideal.

关 键 词：剖宫产 产后镇痛 酮咯酸氨丁三醇 布托啡诺 舒芬太尼 

分 类 号：R719[医药卫生—妇产科学]