Insights into glymphatic system dysfunction and glucose continuum  

作　　者：Tsvetelina Velikova Georgi Vasilev 

机构地区：[1]Medical Faculty,Sofia University St.Kliment Ohridski,Sofia 1407,Bulgaria [2]Clinic of Neurology and Department of Emergency Medicine,UMHAT"Sv.Georgi",Plovdiv 4000,Bulgaria

出　　处：《World Journal of Diabetes》2024年第12期2404-2408,共5页世界糖尿病杂志（英文）

基　　金：Supported by European Union-Next Generation EU,through the National Recovery and Resilience Plan of the Republic of Bulgaria,No.BG-RRP-2.004-0008.

摘　　要：In this article,we comment on an original article published in a recent issue of the World Journal of Diabetes.That observational cross-sectional study focused on investigating the function of the glymphatic system and its clinical correlates in patients with different glucose metabolism states by using diffusion tensor imaging along the perivascular space(DTI-ALPS)index.It was shown that the cerebral glymphatic system may be dysfunctional in patients with type 2 diabetes.Various clinical variables affected the DTI-ALPS index in different glucose metabolism states.In conclusion,the study by Tian et al improves the under-standing of the pathophysiology of diabetes-associated brain damage and pro-vides insights for early diagnosis.

关 键 词：Glymphatic system PREDIABETES Type 2 diabetes mellitus Magnetic reso-nance imaging Diffusion tensor imaging along the perivascular space 

分 类 号：R587.1[医药卫生—内分泌]