Effect of esketamine on reducing postpartum pain and depression  

作　　者：Brandon Lucke-Wold Armin Karamian 

机构地区：[1]Department of Neurosurgery,University of Florida,Gainesville,FL 32608,United States [2]School of Medicine,Shahid Beheshti University of Medical Sciences,Tehran 198396-9411,Tehrān,Iran

出　　处：《World Journal of Clinical Cases》2025年第7期17-20,共4页世界临床病例杂志（英文）

摘　　要：In this editorial,we comment on a recent article by Chen et al,that addressed the effect of intraoperative injection of esketamine on postoperative analgesia and postoperative rehabilitation after cesarean section.Poor management of postcesarean pain is associated with decreased maternal care for the baby,longer hospitalization,and higher risk of developing postpartum depression.Esketamine is a more potent S-enantiomer of ketamine which has shown promising analgesic and antidepressant properties for managing post-cesarean pain and depression in clinical studies.However,due to its potential adverse effects on the neurological and hemodynamic status of patients,it is recommended that its usage in low doses should be limited to cesarean candidates experiencing unbearable pain.Before any recommendation for routine perioperative use of esketamine,more standardized clinical trials are needed to strengthen our existing knowledge of its effectiveness in reducing postpartum pain and depression.

关 键 词：Cesarean section Postpartum pain Postpartum depression Postoperative analgesia Esketamine 

分 类 号：R402[医药卫生—临床医学]