纤支镜肺泡灌洗治疗对急诊重症肺炎合并呼吸衰竭血清学指标的影响  

Effect of Bronchoscopic Alveolar Lavage on Serological Indexes in Emergency Patients with Severe Pneumonia Complicated with Respiratory Failure

作　　者：杨俊英 张伟华[1] 张春玲[1] 牛瑞兰[1] YANG Jun-ying;ZHANG Wei-hua;ZHANG Chun-ling;Niu Rui-lan(Shangqiu First People's Hospital,Shangqiu 476100,Henan Province,China)

机构地区：[1]商丘市第一人民医院,河南商丘476100

出　　处：《罕少疾病杂志》2024年第12期42-44,共3页Journal of Rare and Uncommon Diseases

基　　金：河南省医学科技攻关计划(联合共建)项目(LHGJ2019501)。

摘　　要：目的探讨纤支镜肺泡灌洗技术用在急诊治疗重症肺炎合并呼吸衰竭中的疗效及对患者血清学指标的影响。方法选取2022年9月至2023年8月期间我院急诊科收治的60例重症肺炎合并呼吸衰竭患者的资料,随机分成参照组、治疗组(两组各30例),参照组患者单纯采用药物治疗,治疗组联合纤支镜肺泡灌洗,对比两组患者的治疗效果。结果治疗后,治疗组患者的治疗优良率、HMGB-1、sTREM-1、FEV1、PEF、PaO_(2)/FiO_(2)水平均显著高于参照组患者,差异均有统计学意义(P<0.05);治疗组患者的CD11b阳性的中性粒细胞比例、CRP、PCT、WOB水平低于参照组,差异均有统计学意义(P<0.05)。结论急诊重症肺炎合并呼吸衰竭治疗中给予纤支镜肺泡灌洗的效果十分显著,能改善患者血清学指标、肺功能和呼吸功能,减轻患者不适症状,加速其康复进程。Objective Exploring the efficacy of bronchoscopy bronchoalveolar lavage technique in emergency treatment of severe pneumonia complicated with respiratory failure and its impact on patient serological indicators.Methods Select the data of 60 patients with severe pneumonia complicated with respiratory failure admitted to our emergency department from September 2022 to August 2023,and randomly divide them into a reference group and a treatment group(30 patients in each group).Patients in the reference group were treated with medication alone,while patients in the treatment group were treated with fiberoptic bronchoscopy bronchoalveolar lavage.Compare the treatment effects of the two groups of patients.Results After treatment,the treatment excellent and good rate,HMGB-1,sTREM-1,FEV1,PEF,PaO_(2)/FiO_(2) levels in the treatment group were significantly higher than those in the reference group,with statistical significance(P<0.05).The levels ofCD11B-positive neutrophils、CRP,PCTand WOB in treatment group were lower than those in reference group,with statistical significance(P<0.05).Conclusion The use of bronchoscopic bronchoalveolar lavage in the treatment of emergency severe pneumonia with respiratory failure is highly effective,as it can improve patients'serological indicators,lung function,and respiratory function,alleviate discomfort symptoms,and accelerate their recovery process.

关 键 词：急诊 重症肺炎 呼吸衰竭 纤支镜肺泡灌洗 血清学指标 

分 类 号：R563.1[医药卫生—呼吸系统]