心肌炎儿童MRI表现及心功能生化cTnT、pro-BNP浓度异常的关系研究  

Study on the Relationship between MRI Findings and Abnormal Concentrations of Cardiac Function Biochemical cTnT and Pro-BNP in Children with Myocarditis

作　　者：郑苏萍 马远航 徐恬 ZHENG Su-ping;MA Yuan-hang;XU Tian(Imaging Center,The First Affiliated Hospital of Henan University of Science and Technology,Luo yang471000,Henan Province,China)

机构地区：[1]河南科技大学第一附属医院影像中心,河南洛阳471000

出　　处：《罕少疾病杂志》2024年第12期65-66,71,共3页Journal of Rare and Uncommon Diseases

摘　　要：目的分析心肌炎儿童MRI表现及心功能生化cTnT、pro-BNP浓度异常的关系。方法选取2022年1月至2022年12月期间我院收治的64例心肌炎患儿作为观察组,收集同期在我院接受健康体检结果正常儿童36例作为对照组,所有对象均接受MRI检查,并对血清心肌肌钙蛋白T(cTnT)和N端脑钠肽前体(pro-BNP)进行检测,参考临床诊断结果,分析MRI在心肌炎儿童中的诊断价值及不同心功能生化cTnT、pro-BNP浓度MRI检出情况。结果心脏MRI诊断中42例为阳性,58例为阴性,灵敏度为62.50%,特异度为94.44%,准确率为74.00%,心肌炎心脏MRI诊断约登指数=0.57,kappa值=0.503,吻合度一般;心肌炎患儿cTnT水平达到140 ng/L以上,pro-BNP达到614 ng/L以上检出率明显比cTnT水平低于140 ng/L和pro-BNP水平低于614 ng/L高(P<0.05)。结论通过心脏MRI可以准确检查心肌炎,特别是cTnT、pro-BNP浓度越高的患儿,心脏MRI检出率更高。Objective To analyze the relationship between MRI findings and abnormal concentrations of cardiac function biochemical cTnT and pro-BNP in children with myocarditis.Methods Select 64 children with myocarditis admitted to our hospital from January 2022 to December 2022 as the observation group,and collect 36 children with normal physical examination results in our hospital during the same period as the control group,All subjects underwent MRI examination,and serum cardiac troponin T(cTnT)and N-terminal pro-brain natriuretic peptide(pro-BNP)were detected.Referring to clinical diagnostic results,the diagnostic value of MRI in children with myocarditis and the detection of concentrations of different functional biochemical cTnT and pro-BNP by MRI were analyzed.Results In the cardiac MRI diagnosis,42 cases were positive,58 cases were negative,with a sensitivity of 62.50%,a specificity of 94.44%,and an accuracy of 74.00%.The cardiac MRI diagnosis of myocarditis had a Yoden index of 0.57,a Kappa value of 0.503,and a general degree of anastomosis;The detection rate of cTnT levels above 140 ng/L and pro-BNP levels above 614 ng/L in children with myocarditis was significantly higher than that of cTnT levels below 140 ng/L and pro-BNP levels below 614 ng/L(P<0.05).Conclusion Cardiac MRI can accurately detect myocarditis,especially in children with higher concentrations of cTnT and pro-BNP,and the detection rate of cardiac MRI is higher.

关 键 词：心肌炎 MRI表现 心功能 

分 类 号：R445[医药卫生—影像医学与核医学] R542.2[医药卫生—诊断学]