25(OH)D、FT3在注意力缺陷多动障碍患儿中的表达及临床意义  

Expression of 25(OH)D and FT3 in Children with Attention Deficit Hyperactivity Disorder and Its Clinical Significance

作　　者：韩露 李倩倩 张璐璐 HAN Lu;LI Qian-qian;ZHANG Lu-lu(Rehabilitation Mental Health Center,Kaifeng Children’s Hospital,Kaifeng 475000,Henan Province,China;Intensive Care Unit,Kaifeng Children’s Hospital,Kaifeng 475000,Henan Province,China)

机构地区：[1]开封市儿童医院康复心理保健中心,河南开封475000 [2]开封市儿童医院重症监护室,河南开封475000

出　　处：《罕少疾病杂志》2024年第12期138-139,共2页Journal of Rare and Uncommon Diseases

摘　　要：目的探讨25-羟维生素D(25-hydroxyvitamin D,25(OH)D)、游离三碘甲状腺原氨酸(free triiodothyronine,FT3)在注意力缺陷伴多动障碍(attention deficit hyperactivity disorder,ADHD)患儿中的表达及临床意义。方法回顾性分析2022年5月至2024年1月于本院收治的81例ADHD患儿(试验组)和同期体检健康人群79例(对照组)的临床资料。比较两组25(OH)D、FT3水平;比较ADHD不同严重程度、不同ADHD分型患儿25(OH)D、FT3水平。结果试验组25(OH)D、FT3水平明显低于对照组(P<0.05);ADHD不同严重程度患儿25(OH)D、FT3水平比较:轻度ADHD组>中度ADHD组>重度ADHD组(P<0.05);HIT组25(OH)D、FT3水平均低于CT组、PIT组(P<0.05)。结论25(OH)D、FT3可能参与了ADHD发生、发展,临床可通过检测上述因子对ADHD进行诊断及病情评估。Objective To investigate the expression and clinical significance of 25-hydroxyvitamin D(25(OH)D)and Free Triiodothyronine(FT3)in children with Attention Deficit Hyperactivity Disorder(ADHD).The expression and clinical significance of FT3 in children with ADHD.Methods Clinical data of 81 children with ADHD admitted to our hospital from May 2022 to January 2024(experimental group)and 79 children from healthy population with medical examination during the same period(control group)were retrospectively analysed.Comparison of 25(OH)D and FT3 levels between the two groups;comparison of 25(OH)D and FT3 levels in children with different severity of ADHD and different ADHD subtypes.Results The levels of 25(OH)D and FT3 in the test group were significantly lower than those in the control group(P<0.05);the comparison of the levels of 25(OH)D and FT3 in children with different degrees of severity of ADHD:mild ADHD group>moderate ADHD group>severe ADHD group(P<0.05);and the levels of 25(OH)D and FT3 in the HIT group were lower than those in the CT and PIT groups(P<0.05).Conclusion 25(OH)D and FT3 may be involved in the occurrence and development of ADHD.Clinical diagnosis and assessment of ADHD can be made by testing the above factors.

关 键 词：25(OH)D FT3 注意力缺陷伴多动障碍 

分 类 号：R715.9[医药卫生—妇产科学]