1例急性心梗PCI术后出现左心室附壁血栓的抗凝药学监护  

Personalized Pharmaceutical Monitoring of Left Ventricular Mural Thrombus after PCI in A Case of Acute Myocardial Infarction

作　　者：吕盼 金玉婷 尹丽珍 LV Pan;JIN Yu-ting;YIN Li-zhen(Department of Pharmacy,Tonglu Hospital of Traditional Chinese Medicine,Tonglu 311500,China)

机构地区：[1]杭州市桐庐县中医院药剂科临床药学室,浙江杭州311500

出　　处：《海峡药学》2024年第11期92-95,共4页Strait Pharmaceutical Journal

摘　　要：目的 探讨1例急性心梗经皮冠状动脉介入术(PCI)后出现左心室附壁血栓(Left ventricular wall thrombus,LVT)的个性化药学监护。方法 1例急性心梗PCI术后出现LVT初始给予华法林抗凝治疗后患者手臂及大腿出现大块瘀斑,临床药师协助分析出血原因并制定个性化的治疗建议。结果 医师采纳临床药师建议,患者抗凝治疗3个月后LVT消失。结论 临床药师通过协助临床医师处理分析药物不良反应,开展抗凝药学监护可明显提高急性心梗PCI术后出现LVT患者用药的安全性和有效性。OBJECTIVE Exploring personalized pharmaceutical monitoring for a case of left ventricular wall thrombus(LVT) after PCI for acute myocardial infarction.METHODS One case of acute myocardial infarction after PCI showed LVT.After initial anticoagulation treatment with warfarin,the patient developed large bruises on the arms and thighs.Clinical pharmacists assisted in analyzing the cause of bleeding and developing personalized treatment recommendations.RESULTS The physician followed the advice of a clinical pharmacist and the patient′s left ventricular thrombus disappeared after 3 months of anticoagulation treatment.CONCLUSION Clinical pharmacists assist clinical physicians in handling and analyzing adverse drug reactions,Conducting anticoagulant pharmaceutical monitoring can significantly improve the safety and effectiveness of medication for patients with LVT after PCI for acute myocardial infarction.

关 键 词：急性心梗 左心室附壁血栓 抗凝 药学监护 

分 类 号：R969[医药卫生—药理学]