智能响应性生物材料在组织修复与再生中的应用进展  

Advances in the application of smart responsive biomaterials in tissue repair and regeneration

作　　者：张海峰 郑士亚 程韬 邵翔宇[1] 李俊生[1] ZHANG Haifeng;ZHENG Shiya;CHENG Tao;SHAO Xiangyu;LI Junsheng(Department of General Surgery,Zhongda Hospital Southeast University,Nanjing 210009,China;Department of Oncology,Zhongda Hospital Southeast University,Nanjing 210009,China)

机构地区：[1]东南大学附属中大医院普外科,江苏南京210009 [2]东南大学附属中大医院肿瘤科,江苏南京210009

出　　处：《山东第一医科大学（山东省医学科学院）学报》2024年第12期752-758,共7页Journal of Shandong First Medical University ＆ Shandong Academy of Medical Sciences

基　　金：国家自然科学基金(82303959)。

摘　　要：生物材料在组织修复与再生领域中扮演着至关重要的角色,其应用可显著提高临床治疗效果,并改善患者预后。智能响应性生物材料是一类能够对外界刺激如温度、pH值、光照、电场、磁场以及生物分子等做出响应并产生相应变化的材料,在组织工程中展现出巨大的应用前景。本文将对智能响应性生物材料促进组织修复机制及智能响应机制作一综述,并进一步分析智能响应性生物材料在组织修复与再生过程中的挑战和未来发展方向。In the field of tissue regeneration and repair,biomaterials are essential,and their use can enhance patient outcomes and prognoses.A class of materials known as smart-responsive biomaterials is able to react and change in response to various environmental stimuli,including light,temperature,pH,electric and magnetic fields,and biomolecules.Because of these materials'special qualities,tissue engineering could benefit greatly from their use.An overview of smart response and smart responsive biomaterials'mechanism for encouraging tissue healing will be provided in this study,along with an analysis of the difficulties and potential applications of smart responsive biomaterials in tissue regeneration and repair.

关 键 词：智能响应性生物材料 组织修复 再生医学 

分 类 号：R318.08[医药卫生—生物医学工程]