从中医气化失序探析代谢综合征  

Study on the correlation between disordered gasification of TCM and metabolic syndrome

作　　者：雷晶晶 杨金生[1] 陈曦[1] 张冰晗 姜玉华 刘继法 LEI Jingjing;YANG Jinsheng;CHEN Xi(Institute of Basic Theory of Traditional Chinese Medicine,Chinese Academy of Traditional Chinese Medicine,Beijing 100091,China)

机构地区：[1]中国中医科学院中医基础理论研究所,北京100010

出　　处：《四川中医》2024年第12期43-45,共3页Journal of Sichuan of Traditional Chinese Medicine

基　　金：中国中医科学院科技创新工程项目(CI2021A00104)-现代疾病中医诊疗理论研究模式构建及应用。

摘　　要：本研究探讨了气化失序与代谢综合征(metabolic syndrome,MS)之间的相关性。通过文献整理,探明气化失序是“气变”“乱气”“邪气”的和载体,是一种打破阴阳平衡、脏腑功能失调而诱发的病理状态,具有损神机、坏形体的作用,可诱发“膏变为病”。本文从能量代谢异常和感应功能失调探讨了气化失序诱发MS的发生机制可能与糖脂代谢紊乱、氧化应激下的炎症反应以及信号传导干扰和细胞自噬失常有关,可为MS异病、多病同治提供理论依据,有助于从调节气化的角度预防和治疗MS提供新的思路和策略。This study investigated the association between metabolic syndrome(MS)and gasification disorder.Through literature review,it is proved that the disordering of gasification is the carrier of“qi change”,“chaotic qi”and“pathogenic qi”,and it is a pathological state induced by breaking the balance of Yin and Yang and disturbing the balance of Viscera,which has the effect of damaging the spirit and body,which can induce“Gao into disease”.In this review,we discuss the pathogenesis of MS induced by gasification disorder from the abnormal energy metabolism and sensory dysfunction,which may be related to the disorder of glucose and lipid metabolism,inflammatory response under oxidative stress,signal transduction interference and autophagy disorder.This study can provide theoretical basis for the“simultaneous treatment”and"domination"of MS with multiple diseases.It is beneficial to propose new ideas and strategies for MS prevention and treatment in terms of gasification regulation.

关 键 词：气化失序 代谢综合征 膏 能量代谢 感应功能 

分 类 号：R589[医药卫生—内分泌]