药用植物苯乙醇苷类代谢及其代谢基因的研究进展  

Research Progress on the Metabolism of Phenylethanolamine Glycosides and Their Related Metabolic Genes in Medicinal Plant

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作  者:李祖夏 王路昊 尹崇鑫 乔枫 LI Zuxia;WANG Luhao;YIN Chongxin;QIAO Feng(Key Laboratory of Medicinal Animal and Plant Resources on the Qinghai Tibet Plateau in Qinghai Province,School of Life Sciences,Qinghai Normal University,Xining Qinghai 810008,China;Institute of Plateau Science and Sustainable Development,Qinghai Normal University,Xining Qinghai 810008,China)

机构地区:[1]青海省青藏高原药用动植物资源重点实验室,青海师范大学生命科学学院,青海西宁810008 [2]青海师范大学高原科学与可持续发展研究院,青海西宁810008

出  处:《青海农林科技》2024年第4期45-51,共7页Science and Technology of Qinghai Agriculture and Forestry

基  金:青海省科技厅项目(2021-ZJ-729);青海师范大学大学生创新创业训练项目(qhnucxcy2023056)。

摘  要:苯乙醇苷类是许多药用植物的主要成分之一,目前从药用植物中分离出200多种苯乙醇苷类化合物。该类化合物具有重要的药物活性成分,表现出护肝、抗菌消炎、抗氧化、保护心肌等多种药理功能。结合近年国内外研究,以药用植物中苯乙醇苷代谢途径及其相关酶基因生物学功能进行综述,深入理解这些酶基因对苯乙醇苷化合物代谢物积累的调节作用,为苯乙醇苷类成分积累与调控提供一定的科学参考。Phenylethanoid glycosides were identified as one of the main components in various plants,and over 200 types of phenylethanoid glycoside compounds were isolated from multiple medicinal plants.The pharmaceutical industry recognizes these compounds as crucial active ingredients,exhibiting diverse pharmacological functions such as liver protection,antibacterial and anti-inflammatory properties,antioxidant effects,and myocardial protection.A comprehensive review of phenylethanolamine metabolism pathways and the associated enzyme genes in plants were presented in this study.The aim was to investigate the biological functions of phenylethanolamine metabolism-related enzyme genes and gain a deeper understanding of their regulatory effects on the accumulation of phenylethanolamine metabolites,while also providing a scientific reference for the accumulation and regulation of phenylethanol glycosides.

关 键 词:苯乙醇苷类成分 生物合成途径 代谢酶基因 生物学功能 

分 类 号:R285[医药卫生—中药学] R284.3[医药卫生—中医学]

 

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