关苍术的化学成分及药理作用研究进展  

Research Progress on the Chemical Composition and Pharmacological Effects of Atractylodes japonica

作　　者：付蕾[1] 杜欣柯 林逸君 尹蕊[1] 吴丽红[1] 张超[1] 武千慧 龚缘 贾力维[1] 段艳宁 张基庆[1] 康宇红[1] 徐暘[1] 黄伟 熊迎夏 荣晓惠 FU Lei;DU Xinke;LIN Yijun;YIN Rui;WU Lihong;ZHANG Chao;WU Qianhui;GONG Yuan;JIA Liwei;DUAN Yanning;ZHANG Jiqing;KANG Yuhong;XU Yang;HUANG Wei;XIONG Yingxia;RONG Xiaohui(Heilongjiang University of Chinese Medicine,Harbin 150040,China)

机构地区：[1]黑龙江中医药大学,黑龙江哈尔滨150040

出　　处：《中医药信息》2024年第12期72-87,共16页Information on Traditional Chinese Medicine

基　　金：黑龙江省中医药科研项目(ZHY2020-086);黑龙江中医药大学大学生科技创新项目(2021-12);黑龙江中医药大学药学院本科生科研实习专项基金项目(039372);黑龙江中医药大学优秀青年骨干教师支持计划项目(15041190021);黑龙江中医药大学科研基金面上项目(201738)。

摘　　要：关苍术为菊科苍术属多年生草本植物关苍术的干燥根茎,为东北地区的道地药材,具有多种药理活性。本文对关苍术化学成分和药理作用进行了系统的归纳和总结,发现其主要含有萜类、烯炔类、芳香类、糖苷类、烃类、醇类、醛酮类、酯类和多糖类等化学成分;具有抗炎、抗过敏、抗心肌缺血、抗心律失常、抗溃疡、抗菌、抗病毒、降血糖、利水、抗癌和解毒利胆等药理作用。Atractylodes japonica,the dried rhizome of Asteraceae,is a traditional Chinese medicine widely used in Northeast China.This herb has various pharmacological activities.This paper systematically summarizes the chemical compositions and pharmacological effects of the medicinal.The main chemical constituents include terpenoids,alkynes,aromatics,glycosides,hydrocarbons,alcohols,aldehydes,ketones,esters,and polysaccharides.The pharmacological activities include anti-inflammatory,anti-allergic,anti-myocardial ischemia,anti-arrhythmic,anti-ulcer,anti-bacterial,anti-viral,blood glucose-lowering,diuretic,anti-cancer,detoxifying,and choleretic effects.

关 键 词：关苍术 道地药材 化学成分 药理作用 研究进展 

分 类 号：R284[医药卫生—中药学] R285[医药卫生—中医学]