营养治疗方式在中度重症高脂血症型急性胰腺炎预后比较  

Comparison of nutritional therapy modalities on the prognosis of moderately severe hyperlipidemia-associated acute pancreatitis

作　　者：车根 佟建华 曹曦[2] CHE Gen;TONG Jianhua;CAO Xi(Baotou Medical College,Inner Mongolia University of Science and Technology,Baotou 014040,China;Erdos Central Hospital,Erdos 017000,China)

机构地区：[1]内蒙古科技大学包头医学院,内蒙古包头014040 [2]鄂尔多斯市中心医院,内蒙古鄂尔多斯017000

出　　处：《华北理工大学学报（医学版）》2024年第6期442-446,452,共6页Journal of North China University of Science and Technology：Health Sciences Edition

基　　金：内蒙古自治区卫生健康科技计划项目课题(编号:202201594)。

摘　　要：目的比较采用不同营养方式的中度重症高脂血症型急性胰腺炎(MSHTAP)患者的临床资料及预后差异。方法纳入2022年1月-2024年4月鄂尔多斯市中心医院住院治疗并有完整临床资料的177例MSHTAP患者,依据腹部和肠道耐受情况分为口服营养组(n=118)和管饲营养组(n=59)。两组患者均接受标准化治疗方案。口服营养组早期给予经口肠内营养,管饲营养组则采用经鼻空肠管或胃管肠内营养。比较分析两组患者的人口学特征、实验室指标变化、临床症状缓解时间、住院时长、住院费用及并发症指标。结果管饲营养组白蛋白(ALB)相对口服营养组更低,平均住院时长、腹痛缓解时间长于口服营养组,胰腺外分泌功能不全和新发糖尿病发病率高于口服营养组,差异均有统计学意义(P<0.001)。结论MSHTAP患者口服营养支持较管饲营养支持在远期预后有较好的临床获益。Objective To compare the clinical data and prognosis differences of moderately severe hyperlipidemia-associated acute pancreatitis(MSHTAP)patients receiving different nutritional therapy modalities.Methods A total of 177 MSHTAP patients with complete data who were hospitalized at Erdos Central Hospital from January 2022 to April 2024 were enrolled.Based on abdominal and intestinal tolerance,the patients were divided into an oral nutrition group(n=118)and a tube feeding nutrition group(n=59).Both groups received standardized treatment protocols.The oral nutrition group received early oral enteral nutrition,while the tube feeding nutrition group received enteral nutrition through a nasojejunal tube or nasogastric tube.Demographic characteristics,changes in laboratory indicators,clinical symptom relief time,length of hospital stay,hospitalization costs,and complication indicators were compared and analyzed between the two groups.Results The tube feeding nutrition group had lower albumin(ALB)levels compared to the oral nutrition group.The tube feeding nutrition group also had longer average lengths of hospital stay,longer abdominal pain relief times,and higher incidence rates of exocrine pancreatic insufficiency and new-onset diabetes compared to the oral nutrition group,with statistically significant differences(P<0.001).Conclusion Oral nutritional support provides better clinical benefits in the long-term prognosis for MSHTAP patients compared to tube feeding nutrition.

关 键 词：中度重症急性胰腺炎 高脂血症性急性胰腺炎 肠内营养 管饲营养 

分 类 号：R657.5[医药卫生—外科学]