野鸟携带病原体情况及高通量测序技术研究进展  

Research Progress on Pathogens Carried by Wild Birds and High-throughput Sequencing Technology

作　　者：庞李艳 王红兵 王晓虎 韩银涛 陈晶 陈自强 刘荣启 吴凯 PANG Liyan;WANG Hongbing;WANG Xiaohu;HAN Yintao;CHEN Jing;CHEN Ziqiang;LIU Rongqi;WU Kai(Shenzhen Institute of Quality and Safety Inspection and Testing,Shenzhen Guangdong 518102;Dongguan Animal Disease Prevention and Control Cente,Dongguan Guangdong 523086;Institute of Animal Health,Guangdong Academy of Agricultural Sciences,Guangzhou Guangdong 510640)

机构地区：[1]深圳市质量安全检验检测研究院,广东深圳518102 [2]广东省东莞市动物疫病预防控制中心,广东东莞523086 [3]广东省农业科学院动物卫生研究所,广东广州510640

出　　处：《广东畜牧兽医科技》2024年第6期90-98,共9页Guangdong Journal of Animal and Veterinary Science

基　　金：广东省动物疫病野外科学观测研究站项目(2021B1212050021);广州市科技计划项目(2023B04J0137);深圳市马场蚊媒病毒学本底调查(动卫经合(2023)K10-002);广东省自然资源事务专项资金-生态林业建设项目。

摘　　要：野生鸟类作为生物多样性最为丰富的脊椎动物之一,对维持生态系统平衡起着重要作用。野生鸟类可携带多种病原体,包括病毒、细菌、寄生虫等。尤其是人畜共患病,对人类公共卫生构成潜在威胁。面对疫病传播发展的日益复杂化与不确定性,传统的病原微生物检测方法对于病原学检测存在局限性。而高通量测序技术的出现和技术更新,极大地提升了病原微生物的识别与鉴定能力。因此,为加强对鸟类携带病原体的传播疫病情况的了解,该文着重对野生鸟类携带病原体的流行情况,传统检测方法和高通量测序技术在野生鸟类疫病研究中的应用方面进行综述,以期为科研工作者在探究野生鸟类携带病原体及高通量测序技术在野生动物疫病中的应用提供借鉴和参考。Wild birds,as one of the most diverse vertebrate species,play an important role in maintaining ecosystem balance.Wild birds carry various pathogenic microorganisms,including viruses,bacteria,parasites,etc.Especially zoonotic diseases pose a potential threat to human public health.Faced with the increasingly complex and uncertain development of disease transmission,traditional pathogen detection methods have limitations in pathogen detection.The emergence and technological updates of high-throughput sequencing technology have greatly improved the ability to identify and identify pathogenic microorganisms.Therefore,in order to enhance the understanding of the transmission of diseases by birds carrying pathogenic microorganisms,this article focuses on the prevalence of pathogenic microorganisms carried by wild birds,and reviews the application of traditional detection methods and high-throughput sequencing technology in the study of wild bird diseases.The aim is to provide reference and guidance for researchers in exploring the application of pathogenic microorganisms carried by wild birds and high-throughput sequencing technology in wild animal diseases.

关 键 词：野生鸟类 人畜共患病 高通量测序 宏病毒组 16S rDNA 

分 类 号：S852.65[农业科学—基础兽医学]