中老年人带状疱疹疫苗接种意愿影响因素的Meta分析  

Influencing factors of herpes zoster vaccination intention in middle-aged and elderly people:a Meta-analysis

作　　者：沈馨蕊 王芸芸[1] 熊壮 邹东岑 SHEN Xinrui;WANG Yunyun;XIONG Zhuang;ZOU Dongcen(Guizhou Medical University,Guizhou 561113 China)

机构地区：[1]贵州医科大学,贵州561113

出　　处：《循证护理》2024年第24期4391-4396,共6页Chinese Evidence-Based Nursing

基　　金：2023年度贵州省卫生健康委员会科学技术基金项目,编号:gzwkj2023-248;2022年贵州医科大学护理学科教研与科研项目,编号:YJ22019。

摘　　要：目的:系统评价中老年人带状疱疹疫苗接种意愿的影响因素,为制定疫苗接种策略提供参考。方法:计算机检索PubMed、the Cochrane Library、EMbase、Web of Science、万方数据库、维普数据库、中国知网、中国生物医学文献数据库中关于中老年人带状疱疹疫苗接种意愿影响因素的横断面研究,检索时限自建库至2023年12月18日,由2名研究者独立进行文献筛选、资料提取和质量评价,采用RevMan 5.4软件进行Meta分析。结果:共纳入10篇文献,涉及2058884例中老年人。Meta分析结果显示,带状疱疹病毒感染风险[OR=1.61,95%CI(1.50,1.74),P<0.00001]、专业人员的建议[OR=5.92,95%CI(3.97,8.83),P<0.00001]、接种过至少1种推荐接种的疫苗[OR=3.27,95%CI(2.09,5.01),P<0.00001]、知晓带状疱疹疫苗的存在[OR=2.89,95%CI(2.17,3.85),P<0.00001]是中老年人接种带状疱疹疫苗意愿的促进因素,而担忧[OR=2.07,95%CI(1.51,2.83),P<0.00001]是其阻碍因素。结论:现有证据表明,感染风险、专业人员的建议、接种过至少1种推荐接种的疫苗、知晓带状疱疹疫苗存在是中老年人带状疱疹疫苗接种意愿的促进因素,尚不能证明学历、年龄和知晓他人患病等因素对中老年人带状疱疹疫苗接种意愿的影响。Objective:To systematically evaluate the influencing factors of herpes zoster vaccination intention in middle-aged and elderly people,and provide reference for formulating vaccination strategy.Methods:Cross-section studies on the influencing factors of herpes zoster vaccination intention in middle-aged and elderly people were searched by computer,including PubMed,the Cochrane Library,EMbase,Web of Science,WanFang Database,VIP,CNKI,and CBM.The search period was self-established until December 18,2023.Literature screening,data extraction and quality evaluation were conducted independently by two researchers,and Meta-analysis was performed using RevMan 5.4 software.Results:A total of 10 articles were included,involving 2058884 middle-aged and elderly patients.Meta-analysis showed that the risk of herpes zoster virus infection(OR=1.61,95%CI 1.50-1.74,P<0.00001),professional recommendation(OR=5.92,95%CI 3.97-8.83,P<0.00001),have received at least one recommended vaccine(OR=3.27,95%CI 2.09-5.01,P<0.00001),know the existence of the herpes zoster vaccine(OR=2.89,95%CI 2.17-3.85,P<0.00001)was the promoting factor for the willingness of middle-aged and elderly people to receive herpes zoster vaccine,while worry(OR=2.07,95%CI 1.51-2.83,P<0.00001)was the hindrance factor.Conclusions:Existing evidence shows that risk of infection,professional recommendation,having received at least one recommended vaccine,and knowing the existence of the herpes zoster vaccine are the promotion factors of shingles vaccination intention in middle-aged and elderly people.The influence of education,age,and knowledge of other people′s illness on shingles vaccination intention in middle-aged and elderly people cannot be proved.

关 键 词：中老年人 带状疱疹 疫苗 影响因素 系统评价 META分析 循证护理 

分 类 号：R186[医药卫生—流行病学]