Regulation of graphdiyne-based nanozymes with enhanced oxidaselike activity by cobalt and nitrogen codoping  

作　　者：Jiali Liu Xiaoli Wang Yongfu Lian Xue Wang Xiuxiu Wang Xingfa Gao Baoyun Sun Xihong Guo 

机构地区：[1]CAS Key Laboratory for Biomedical Effects of Nanomaterial&Nanosafety,Institute of High Energy Physics,Chinese Academy of Science,Beijing 100049,China [2]Key Laboratory of Functional Inorganic Material Chemistry,Ministry of Education,School of Chemistry and Materials Science,Heilongjiang University,Harbin 150080,China [3]Laboratory of Theoretical and Computational Nanoscience,National Center for Nanoscience and Technology,Beijing 100190,China [4]University of Chinese Academy of Sciences,Beijing 100049,China

出　　处：《Nano Research》2025年第1期21-29,共9页纳米研究（英文版）

基　　金：supported financially by the National Key Research and Development Program of China(Nos.2022YFA1205900 and 2018YFA0703504);the Directional Institutionalized Scientific Research Platform relied on Beijing Synchrotron Radiation Facility of Chinese Academy of Sciences。

摘　　要：The development of nanozymes with excellent intrinsic oxidase-like activity and specificity has received increasing interest.Graphdiyne(GDY)could be a promising choice for designing nanozymes with enhanced oxidase(OXD)-like activity due to its unique structure and properties.Herein,Co-N-GDY with high OXD activity but no peroxidase(POD)activity was synthesized by codoping of cobalt(Co)and nitrogen(N)into GDY and compared with other GDY-based nanozymes(including GDY,Co-GDY,and N-GDY).Upon analyzing the doping effect of Co and N on the OXD-like and POD-like activities,we found that the combination of Co and N in GDY played a significant role in enhancing the OXD-like activity,and even reversed the POD-like activity of N-GDY to OXD-like activity of Co-N-GDY.The electrochemical experiment and the theoretical calculations provided an explanation for the mechanism and showed that the activity was closely linked to the reduction ability of O_(2) or H_(2)O_(2) on the nanozyme substrates,which was determined by the ratedetermining step of the catalytic reaction.

关 键 词：nanozymes oxidase-like activity graphdiyne heteroatom doping REGULATION 

分 类 号：O64[理学—物理化学]