PtCu dendroframe octahedrons:Enhancing peroxidase-like activity and antibacterial efficiency through structural evolution  

作　　者：Ri Feng Jiuyi Hu Liangjun Wang Jiayu Xu Jiajia Li Zeeshan Ahmad Shaohui Zheng Muhammad Farhan Farid Wenjing Liu Faisal Saleem 

机构地区：[1]Key Laboratory of Flexible Electronics(KLOFE),Institute of Advanced Materials(IAM)and School of Flexible Electronics(Future Technologies),Nanjing Tech University,Nanjing 211816,China

出　　处：《Nano Research》2025年第1期100-106,共7页纳米研究（英文版）

基　　金：supported by the National Natural Science Foundation of China(Nos.22175087 and 22075133);the Jiangsu Provincial Funds(No.BX2022013)for the financial support.

摘　　要：Nanozymes,which possess enzyme-like catalytic activity,are attractive alternatives to natural enzymes.Their activity is largely dependent on the structure of the material.However,challenges remain in optimizing the structure-activity relationship.This work explores the synthesis and utilization of PtCu nanostructures(NSs),focusing on their peroxidase(POD)-like properties and their potential as antibacterial agents.We developed PtCu dendrites that transform into unique dendroframe octahedrons(DFOs)and subsequently stabilize into solid octahedrons with unusual growth behaviour.The intermediate DFO,showed higher POD-like activity in comparison to other shapes of PtCu NSs.The DFOs also have the better ability to consume glutathione,thus enhancing their sterilization effect.Furthermore,we demonstrate the effectiveness of these PtCu DFOs as powerful antibacterial agents.This work provides valuable information on shape dependent activities of PtCu NSs in the field of biomedicine.

关 键 词：nanozymes ANTIBACTERIALS PEROXIDASE PtCu dendroframe octahedrons DENDRITES 

分 类 号：O64[理学—物理化学]