单纯疱疹的反射式共聚焦显微镜特征分析  

The Characteristic Analysis of Herpes Simplex by Reflectance Confocal Microscopy

作　　者：马玲[1] 陈红英[1] Ma Ling;Chen Hongying(Wuhan First Hospital,Wuhan 430022,China)

机构地区：[1]武汉市第一医院,湖北武汉430022

出　　处：《湖北成人教育学院学报》2024年第6期124-128,共5页Journal of Hubei Adult Education Institute

基　　金：湖北省武汉市卫生健康委员会课题“女性生殖道疾病与病毒群落多样性相关性研究”(WX20B17)。

摘　　要：目的:探讨单纯疱疹的反射式共聚焦显微镜特征。方法:对39例经聚合酶链反应确诊的单纯疱疹患者进行反射式共聚焦显微镜检测,分析单纯疱疹的反射式共聚焦显微镜图像特征。结果:有37例患者能发现表皮内水疱,32例水疱内能发现棘层松解细胞和多核表皮巨细胞,另外5例水疱病人仅见水疱内炎细胞。结论:水疱内棘层松解细胞或多核表皮巨细胞可以作为单纯疱疹反射式共聚焦显微镜检查的重要诊断依据。Objective:To investigate the characteristic of herpes simplex by reflectance confocal microscopy(RCM).Methods:Thirty-nine patients with herpes simplex diagnosed by polymerase chain reaction were examined by RCM,and the characteristics of RCM images were analyzed.Results:Intraepidermal blisters were found in 37 patients,acantholytic cells and multinucleated epidermal giant cells were found within the blisters in 32 cases,while only inflammatory cells within the blisters were seen in the other 5 patients with blisters.Conclusion:Acantholytic cells or multinucleated epidermal giant cells in blisters can be be an important diagnostic basis for herpes simplex by RCM.

关 键 词：单纯疱疹 反射式共聚焦显微镜 棘层松解细胞 

分 类 号：R752.1[医药卫生—皮肤病学与性病学]