不同地域应激性心肌病诊治现况分析  

Diagnosis and Treatment of Takotsubo Syndrome in Different Regions in China

作　　者：阿依努尔·麦合木提 罗晓亮[2] 王舸[3] 刘永[1] 王勇[1] 程慧[1] 张峻[2] Ayinuer Maihemuti;LUO Xiaoliang;WANG Ge;LIU Yong;WANG Yong;CHENG Hui;ZHANG Jun(Department of Cardiology,People's Hospital of Xinjiang Uygur Autonomous Region,Urumqi 830001,Xinjiang,China;Department of Cardiology,National Center for Cardiovascular Diseases and Fuwai Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Bejing 100037,China;Department of Cardiology,Urumqi Hospital of Traditional Chinese medicine,Urumqi 830000,Xinjiang,China)

机构地区：[1]新疆维吾尔自治区人民医院心脏与泛血管医学诊疗中心,新疆乌鲁木齐830001 [2]中国医学科学院北京协和医学院国家心血管病中心阜外医院冠心病中心,北京100037 [3]乌鲁木齐市中医院心病科,新疆乌鲁木齐830000

出　　处：《中国分子心脏病学杂志》2024年第5期6352-6356,共5页Molecular Cardiology of China

摘　　要：目的比较应激性心肌病(TTS)在国内不同地域的诊断和治疗现状,加深对TTS的理解。方法回顾性分析新疆维吾尔自治区人民医院、乌鲁木齐市中医院和中国医学科学院阜外医院在2015年7月至2023年8月期间收治并确诊为TTS患者的临床资料,应用组间和组内比较分析不同地域TTS诊断和治疗情况。结果乌鲁木齐地区医院7例、阜外医院23例TTS患者入选本研究,与阜外医院诊断组患者相比,乌鲁木齐地区医院诊断组确诊患者数量占同期重症监护室收治急性冠脉综合征患者比例更低(0.09%比0.28%,P=0.009),年龄更轻[(49.4±17.4)岁比(64.9±12.1)岁,P=0.013],能够接受心脏磁共振检查比例更低(0比73.91%,P=0.001)。组内自身比较恢复期N末端脑钠肽前体水平与就诊时检测水平有明显下降,恢复期左室射血分数较确诊时有明确回升,差异有统计学意义(P均<0.05)。出院带药方面(血管紧张素转换酶抑制剂、β受体阻滞剂)两地TTS患者差异无统计学意义(P>0.05)。结论与阜外医院诊断为TTS的患者情况相比,乌鲁木齐地区医院诊断率偏低,确诊TTS患者流行病学(如年龄、发病诱因)亦有所不同,接受心脏磁共振检查比例低。Objective To compare the diagnosis and treatment status of Takotsubo syndrome(TTS)in different regions of China.Methods The clinical data of patients with TTS who were admitted to Urumqi Regional Hospital(Xinjiang Uygur Autonomous Region People′s Hospital and Urumqi Hospital of Traditional Chinese Medicine)and Fuwai Hospital of Chinese Academy of Medical Sciences(Beijing)from July 2015 to August 2023 were retrospectively analyzed.The diagnosis and treatment of TTS in different regions were compared between groups and within groups.Results There were 7 patients from Urumqi Regional Hospital and 23 TTS patients from Fuwai Hospital enrolled in this study.Compared with the patients in the diagnosis group of Fuwai Hospital,the age of the patients in the group of Urumqi Regional Hospital was younger[(49.4±17.4)years vs(64.9±12.1)years,P=0.013],and the proportion of patients who could receive cardiac magnetic resonance examination was lower(0 vs 73.91%,P=0.001).The number of confirmed patients accounted for a lower proportion of acute coronary syndrome patients admitted to the cardiac care unit during the same period(0.09%vs 0.28%,P=0.009).The level of N-terminal pro-brain natriuretic peptide in the convalescent period was significantly lower than that detected at the time of admitted,and the left ventricular ejection fraction in the convalescent period was significantly higher than that at the time of admitted,with statistical significance(all P<0.05).There was no significant difference in discharge drugs(ACEI,β-blockers)between the two groups(P>0.05).ConclusionCompared with the group of patients diagnosed with TTS in Fuwai Hospital,the diagnosis rate of hospitals in Urumqi Regional is lower,and the epidemiology(such as age and pathogenesis)of patients diagnosed with TTS is also different,and the proportion of patients receiving magnetic resonance examination is low.

关 键 词：应激性心肌病 不同地域 临床特征 

分 类 号：R542.2[医药卫生—心血管疾病]