颈椎有限元模型及材料特征的文献分析  

Literature analysis of finite element model and material characteristics of cervical vertebra

作　　者：符碧峰 姜星羽 张超[1] 苏瑾[1] 杨光[1] 刘爱峰[1] 高玉萍 王平[1] 李远栋[1] Fu Bifeng;Jiang Xingyu;Zhang Chao;Su Jin;Yang Guang;Liu Aifeng;Gao Yuping;Wang Ping;Li Yuandong(Regional Center of Traditional Chinese Medicine Orthopedics and Traumatology,State Administration of Traditional Chinese Medicine,National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion,Department of Orthopedics and Traumatology,First Teaching Hospital of Tianjin University of Traditional Chinese Medicine,Tianjin 300381,China;School of Traditional Chinese Medicine,Tianjin University of Traditional Chinese Medicine,Tianjin 301617,China)

机构地区：[1]天津中医药大学第一附属医院骨伤科,国家中医针灸临床医学研究中心,国家中医药管理局区域中医骨伤科诊疗中心,天津300381 [2]天津中医药大学中医学院,天津301617

出　　处：《国际生物医学工程杂志》2024年第5期463-471,共9页International Journal of Biomedical Engineering

基　　金：国家中医药管理局中医药循证能力建设(2019XZZX-GK006);天津中医药大学第一附属医院“拓新工程”(201908);天津市教委资助项目(津教工[2016]3号);天津中医药大学骨伤研究所开放课题(2024GSZ02)。

摘　　要：目的统计颈椎有限元模型及相应材料特征的频次、数值和属性以及边界设定,为有限元模型在颈椎病研究中的应用提供参考。方法检索2013年1月至2023年12月中国知网、万方和维普数据库以及PubMed、Web of Science和Embase数据库中与颈椎相关有限元模型文献,质量评估后进行人工筛选,对纳入文献中颈椎有限元模型的数据来源、应用分类以及颈椎椎体、颈椎椎间盘、颈椎韧带的材料属性(杨氏模量和泊松比)和边界条件的设置进行统计分析。结果最终纳入102篇文献。颈椎有限元模型均来源于医学影像重建建模技术,以计算机断层扫描和核磁共振成像技术为主。在102个颈椎模型中,C3~C7(下颈段)模型频次(19个)最高。颈椎椎体皮质骨、松质骨、后部结构的杨氏模量分别设置为12000或10000、440、3600 MPa左右,泊松比主要设置为0.29或0.30、0.29、0.29左右。颈椎椎间盘终板、髓核、纤维环的杨氏模量分别集中在500或2000、1、100 MPa左右,泊松比分别设置为0.40、0.50、0.40左右。颈椎前纵韧带、后纵韧带、横韧带、黄韧带、棘间韧带、关节囊韧带、关节软骨的杨氏模量分别设置为30、20、20、6~10、4~8、10或20、10 MPa左右,泊松比分别设置为0.30、0.30、0.30、0.30、0.30、0.40、0.30左右。上颈段齿突间韧带、覆膜、十字韧带、项韧带、翼状韧带的杨氏模量分别设置为10、10、10或20、20、5 MPa左右,泊松比均设置为0.30左右。头部重量设置以50、74、100 N多见。结论颈椎有限元模型在颈椎病研究中具有重要价值,但在材料属性赋值、网格划分以及模型验证等方面仍需进一步优化,以提高模型的准确性和临床适用性。Objective To provide references for the application of finite element model in the study of cervical vertebra by statistically analysing the frequency,numerical value,properties,and boundary setting of the finite element model and the corresponding material features as well as boundary settings in the literature.Methods The literature on cervical vertebra-related finite element models was collected from CNKI,Wanfang,VIP,PubMed,Web of Science,and Embase databases from January 2013 to December 2023.The quality assessment was followed by manual screening.The data sources,application classification,material properties(Young’s modulus and Poisson’s ratio),and boundary conditions of cervical vertebra,cervical intervertebral,and cervical ligaments were statistically analyzed.Results A total of 102 papers were included.The finite element models of the cervical vertebra were derived from medical image reconstruction modeling techniques,predominantly CT plain scan and magnetic resonance imaging.Among the 102 cervical vertebra models,the C3-C7(lower cervical segment)model appeared with the highest frequency(19).The Young’s modulus of the cortical bone,cancellous bone,and posterior structure of cervical vertebrae were set at about 12000 or 10000,440,and 3600 MPa,respectively,and the Poisson’s ratios were mainly set at about 0.29 or 0.30,0.29,and 0.29.The Young’s modulus of the cervical intervertebral disc endplate,nucleus pulposus,and annulus fibrosus were concentrated around 500 or 2000,1,and 100 MPa,respectively,and the Poisson’s ratios were set at about 0.40,0.50,and 0.40,respectively.The Young’s modulus of the anterior longitudinal ligament,posterior longitudinal ligament,transverse ligament,ligamentum flavum,interspinous ligament,capsular ligament,and articular cartilage of the cervical spine were set around 30,20,20,6-10,4-8,10 or 20,10 MPa,and the Poisson’s ratios were set at aoubt 0.30,0.30,0.30,0.30,0.30,0.40,and 0.30,respectively.The Young’s modulus of the upper cervical interdental ligament,lamin

关 键 词：颈椎 有限元模型 材料特征 文献分析 

分 类 号：R318.08[医药卫生—生物医学工程] G353.1[医药卫生—基础医学]